<center>NFL Point Spreads For Week 12 - Week Twelve NFL Football Point Spread - NFL Spreads 11/21 - 11/25, 2013</center>
| Date & Time | Favorite | Spread | Underdog |
| 11/21 8:25 ET | New Orleans | -9.5 | At Atlanta |
| 11/24 1:00 ET | At Detroit | -9 | Tampa Bay |
| 11/24 1:00 ET | At Houston | -10 | Jacksonville |
| 11/24 1:00 ET | At Green Bay | -5 | Minnesota |
| 11/24 1:00 ET | At Kansas City | -5 | San Diego |
| 11/24 1:00 ET | Carolina | -4 | At Miami |
| 11/24 1:00 ET | At Cleveland | -2 | Pittsburgh |
| 11/24 1:00 ET | At St. Louis | -1 | Chicago |
| 11/24 1:00 ET | At Baltimore | -3.5 | NY Jets |
| 11/24 4:05 ET | At Oakland | -1 | Tennessee |
| 11/24 4:05 ET | At Arizona | -2 | Indianapolis |
| 11/24 4:25 ET | At NY Giants | -2.5 | Dallas |
| 11/24 8:30 ET | Denver | -3 | At New England |
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| 11/25 8:40 ET | San Francisco | -5 | At Washington |
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