Epistane

bigdaddyo1617

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What is Epistane?

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epistane-chemical-structure.jpg
Fig 1. Epistane Chemical Structure

Chemical Structure: 2a,3a-epithio-17a-methyl-5a-androstan-17b-ol. Epistane has been mistaken as an anti-E at times, although it does not cause Estrogen related side effects and has been reported by users to lower Estrogen, it should not be confused as a pure AI (Aromatase Inhibitor) compound. For the Bodybuilder and trained Athlete, Epistane works as a Anabolic agent that delivers dry, lean muscle gains, and works great for cutting as well. Epistane is much more Anabolic than most people realize and is often under estimated because it is an analogue of an anti-estrogen drug used in Japan. This has caused some people to mistakenly think Epistane has the same properties, yet that is not the case. It is true that Epistane should never convert to the illegal Pheraplex.

The only reason this ProHormone got a bad reputation for converting to a banned substance while sitting in storage for too long, is because some of the “cloned” Epistane products were using 17alpha-methyl 2beta,3beta-epithio 5alpha-androstane, instead of the real true compound: 2a,3a-epithio-17a-methyl-5a-androstan-17b-ol., which should never convert to Pheraplex . Epistane is not just a Pro-hormone, it is already a very powerful active compound that attaches to and activates Androgen Receptor sites. Epistane is a designer hormone, designed to give you the very best Anabolic effects with limited side-effects from Androgens.


Why is Epistane know as a mild compound?
Epistane causes muscle growth, without being too harsh of an Androgen, thus avoiding side-effects like hairloss and bad acne. Epistane’s mild Androgenic effects, with heavy anabolic effects can be explained by taking a closer look at it’s “Myotropic Ratio”, which is a more technical term used to explain the different in how each hormone acts in the body. When it comes to Epistane, it’s “Mytotropic Ratio” is in range of other hormones like Oxandrolone(Anavar) in that it is way more Anabolic than Androgenic when attaching to receptor sites in the muscle cells and other places. In more technical terms, when compared to other popular prosteroids on paper, Epistane is 15 times more myotrophic than Helladrol and a whopping 20 times more myotrophic than Pro-Magnon. It has a vastly superior “myotrophic ratio” of 12 whereas H-drol has a myotrophic ratio of 2.6 and Pro-Magnon has a myotrophic ratio of only 1.1. In layman’s terms, on a milligram-per-milligram basis, Epistane is far less likely (4.62x less like than H-drol and 10.91x less likely than Pro-Magnon) to induce undesirable, androgenic mediated type side effects such as acne and hair loss.


Keep in mind that the above statement is dose related as Epistane is a very strong prosteroid. If you ran a cycle of Epistane with H-drol(more than 75mg) doses, you would experience serious and undesirable side-effects. Epistane is already very strong and doses of 30-40mg a day are all that’s needed to induce very desirable results. For more experienced users some may go as high as 60mg.


How does Epistane increase Mass?
Epistane binds to androgen receptors in skeletal muscle cells and muscle stem cells. When it binds to the receptor site it creates a signal to the cell, telling it to increase protein synthesis and nitrogen retention, thus growth of the cell is certain… Epistane also has an effects on muscle stem cells, which is a very important part of it’s actions since those Muscle Stem cells will actually change and fuse with your active adult skeletal muscles, thus increasing the muscles potential for growth and repair and importantly the most desired effect to those using Epistane: an increase in muscle mass. Epistane has been used as a solid mass builder, but it has a great place in any cutting cycle as well.. In the presence of Androgens the stem cells ability to form new fat cells are greatly hindered. Since this occurs, you now have increased stem cell conversion to muscle cells and a decrease in the conversion of stem cells to fat cells, giving you a more positive effect of nutrition and training, This is perhaps the main reason why Epistane is so effective, even on bulking cycle, because the fat gain is very minimal. As with most methylated steroids, the half life requires split dosing, and to increase its bioavailability I suggest taking it with foods containing fat.


What to watch out for.
Epistane will have a negative impact on good cholesterol, blood lipids, blood pressure and the liver, but at lower dosages of 30mg to 50mg and short cycles of 3-4 weeks, you should worry very little in the way of negative sides. Epistane being largely anabolic is very likely to cause some lethargy but it does not convert to estrogen. There have been some mistaken reports though lots of forums where users report bloat on Epistane. This is likely because they are using the inferior cloned product, containing the earlier mentioned compound written in italics further up this page 17alpha-methyl 2beta,3beta-epithio 5alpha-androstane. This compound is the one that is used to convert to the now banned Pheraplex, which is a very wet Steroid. Real Epistane should not convert to this compound and should always be a very dry, lean muscle gainer.


As mentioned earlier, it is not and anti-e but it can noticeably dry you out. This occurs partly because of the shift in the testosterone/ estrogen ratio. Epistane can’t convert to estrogen or DHT, so its affects will be largely anabolic which is great for recovery and nutrient repartitioning (like in a Recomp Cycle), and considerable amounts of fat loss are often reported by users after only a 2 weeks of use. Muscle mass gains of 6-10LBS are an average gain on a 4-6 week cycle.


THE WAY TO CYCLE EPISTANE
On it’s own, Epistane will create very dramatic results, mainly for the Bodybuilder new to the world of anabolics, where his body is not yet holding an unnatural amount of musculature. Epistane alone will not only maintain but grow even further mass on the new user. The experienced Bodybuilder with 3 to 4 cycles already completed, would see more dramatic gains by stacking Epistane along with other compounds for bigger gains in lean mass, and more dramatic fat loss. Epistane stacks well in any cycle and with any anabolic steroids. It generally does not have negative interactions with other compounds. Testosterone, Deca Durabolin, Trenbolone, Trenavar or even Dianabol can all be stacked with Epistane.


When cutting, it provides help in burning fat and the assurance that muscle mass will be spared at times of dieting. This ensures that only fat will be burned to make up for the caloric deficit. Epistane is very potent anti-catabolic agent during cutting, and can be found in this cycle: OxandroVar the one-bottle stack of Prohormones, Prosteroids and Analouges for the perfect cutting cycle. For body re-composition, or “Recomp Cycles”, Epistane’s ability to help decrease fat gains and increase muscle mass make it a really key ingredient to help shift body composition towards a lower boy-fat% while still keeping or gaining body-weight in the form of solid mass. Stacked together with Trenavar and Methyl-diaz in the PrimobolDx formulation, it creates the perfect environment to run a body re-composition program where fat storage can be mobilized for energy, while muscle cells increase protein synthesis and nitrogen retention
 
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lol, yeah lemme see if i can't fix that up, cause i hate reading run ons
 
I'm the king of epistane. Literally my favorite muscle builder of all time. This article got most of it right - which is surprising since it is very misunderstood.
 
"If you ran a cycle of Epistane with H-drol(more than 75mg) doses, you would experience serious and undesirable side-effects." Untrue IMO Hdrol needs to be run @ 100mg+ I ran the actual methyl colestobol (Spelling ?) version of it @ 100mg 7 weeks no sides.
 
misunderstood how bro?
The whole piece about how it is an anti estrogen - it's not at all! I think it aromatizes somehow. It can't directly aromatize chemically, but estrogen does increase on it and you do have to watch for gyno. It is a methylated ai from Japan. We all know the methyl group changes everything about a compound (examples such as masteron to superdrol or EQ to dbol show this to be true). Also, the prohormone companies that originally made it suggested that it be run in 20-30mg ed dosages which could probably be run for 6 months safely. In order to "run" it, 60+ mg ed is necessary.
 
The whole piece about how it is an anti estrogen - it's not at all! I think it aromatizes somehow. It can't directly aromatize chemically, but estrogen does increase on it and you do have to watch for gyno. It is a methylated ai from Japan. We all know the methyl group changes everything about a compound (examples such as masteron to superdrol or EQ to dbol show this to be true). Also, the prohormone companies that originally made it suggested that it be run in 20-30mg ed dosages which could probably be run for 6 months safely. In order to "run" it, 60+ mg ed is necessary.

I agree bro. I loved epi but I definitely experienced estrogenic sides with it, and that was one of the few times I didnt have anything including test running with it.
 
@fstr03svtcobra hello brother, wanted to send you a PM in regards of info on Epi. Can't seem to get thru seems your inbox is full. Don't know if I could ask right here, please let me know
 
Hello there fstr03svtcobra, I'm trying to figure out what to run for my next cycle. I have done 4 cycles already and my last one was Test prop, Tren ace and Winstrol which made me get good gains. Tren is harsh on me because of insominia and loss of cardio so I'm looking to run another compound. I'm intrigued with Trestolone Ace but I'm no pro and don't know if I could deal with Gyno correctly. So I got interested in Epi, I'd like to know which would be a good protocol and PCT if you can help me out.

Can you run it with Winny and test prop? would you need an AI on cycle? Can you run Epi for 12 weeks? Does it come only in Oral form or is there an injectable?

I am 42 years old, 215 pounds, 6'1'' 14 %bodyfat

thanks anticipated for your help,
 
Hello there fstr03svtcobra, I'm trying to figure out what to run for my next cycle. I have done 4 cycles already and my last one was Test prop, Tren ace and Winstrol which made me get good gains. Tren is harsh on me because of insominia and loss of cardio so I'm looking to run another compound. I'm intrigued with Trestolone Ace but I'm no pro and don't know if I could deal with Gyno correctly. So I got interested in Epi, I'd like to know which would be a good protocol and PCT if you can help me out.

Can you run it with Winny and test prop? would you need an AI on cycle? Can you run Epi for 12 weeks? Does it come only in Oral form or is there an injectable?

I am 42 years old, 215 pounds, 6'1'' 14 %bodyfat

thanks anticipated for your help,
There is no injectible but you could always order epi powder and make it yourself (although I would not do that because it has to be very sterile and would need to be water based). I wouldn't run epi for 12 weeks on a cycle though. That's something I might do in addition to trt at maybe 10 mg ed or 20mg on just training days for a little boost if your body is already healthy (if not, recover). Since you are doing pct, it doesn't sound like you are on trt. Your pct should never change based on the compounds used in your cycle. So whatever worked last time should work again. I would not run it with winny. I've never taken winstrol, but pick one or the other. If you choose epi, run it at the beginning or middle of your cycle at 60mg ed for 6 weeks. I've done that before with great success (in the gym and with returned bloodwork). You will have to watch for gyno. Epistane has given me and lots of my buddies gyno scares. Its "anti-estrogen" properties are a complete internet myth. Hope that helps.
 
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