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    Default Proviron, Stacking and Use:

    PROVIRON -


    Pharmaceutical Name: Mesterolone
    Chemical structure: 1 alpha-methyl-17 beta-hydroxy-5 alpha-androstan-3-one


    Effective dose: 25-100 mg / day orally
    Average Street-price: $0.80 - 1.50 per 25 mg tab
    Available Doses: 10, 20, 25 and 50 mg tabs


    Characteristics:


    Mesterolone is an orally active, 1-methylated DHT. Like Masteron, but then actually delivered in an oral fashion. DHT is the conversion product of testosterone at the 5-alpha-reductase enzyme, the result being a hormone that is 3 to 4 times as androgenic and is structurally incapable of forming estrogen. One would imagine then that mesterolone would be a perfect drug to enhance strength and add small but completely lean gains to the frame. Unfortunately there is a control mechanism for DHT in the human body. When levels get too high, the 3alpha hydroxysteroid dehydrogenase enzyme converts it to a mostly inactive compound known as 3-alpha (5-alpha-androstan-3alpha,17beta-diol), a prohormone if you will. It can equally convert back to DHT by way of the same enzyme when low levels of DHT are detected. But it means that unless one uses ridiculously high amounts, most of what is administered is quite useless at the height of the androgen receptor in muscle tissue and thus mesterolone is not particularly suited, if at all, to promote muscle hypertrophy.


    Proviron has four distinct uses in the world of bodybuilding. The first being the result of its structure. It is 5-alpha reduced and not capable of forming estrogen, yet it nonetheless has a much higher affinity for the aromatase enzyme (which converts testosterone to estrogen) than testosterone does. That means in administering it with testosterone or another aromatizable compound, it prevents estrogen build-up because it binds to the aromatase enzyme very strongly, thereby preventing these steroids from interacting with it and forming estrogen. So Mesterolone use has the extreme benefit of reducing estrogenic side-effects and water retention noted with other steroids, and as such still help to provide mostly lean gains. Its also been suggested that it may actually downgrade the actual estrogen receptor making it doubly effective at reducing circulating estrogen levels.


    The second use is in enhancing the potency of testosterone. Testosterone in the body at normal physiological levels is mostly inactive. As much as 97 or 98 percent of testosterone in that amount is bound to sex hormone binding globulin (SHBG) and albumin, two proteins. In such a form testosterone is mostly inactive. But as with the aromatase enzyme, DHT has a higher affinity for these proteins than testosterone does, so when administered simultaneously the mesterolone will attach to the SHBG and albumin, leaving larger amounts of free testosterone to mediate anabolic activities such as protein synthesis. Another way in which it helps to increase gains. Its also another part of the equation that makes it ineffective on its own, as binding to these proteins too, would render it a non-issue at the androgen receptor.


    Thirdly, mesterolone is added in pre-contest phases to increase a distinct hardness and muscle density. Probably due to its reduction in circulating estrogen, perhaps due to the downregulating of the estrogen receptor in muscle tissue, it decreases the total water build-up of the body giving its user a much leaner look, and a visual effect of possessing "harder" muscles with more cuts and striations. Proviron is often used as a last-minute secret by a lot of bodybuilders and both actors and models have used it time and again to deliver top shape day in day out, when needed. Like the other methylated DHT compound, drostanolone, mesterolone is particularly potent in achieving this feat.


    Lastly Proviron is used during a cycle of certain hormones such as nandrolone, with a distinct lack of androgenic nature, or perhaps 5-alpha reduced hormones that don't have the same affinities as DHT does. Such compounds, thinking of trenbolone, nandrolone and such in particular, have been known to decrease libido. Limiting the athlete to perform sexually being the logical result. DHT plays a key role in this process and is therefore administered in conjunction with such steroids to ease or relieve this annoying side-effect. Proviron is also commonly prescribed by doctors to people with low levels of testosterone, or patients with chronic impotence. Its not perceived as a powerful anabolic, but it gets the job done equally well if not better than other anabolic steroids making it a favorite in medical practices due to its lower chance of abuse.


    Mesterolone is generally well liked nonetheless as it delivers very few side-effects in men. In high doses it can cause some virilization symptoms in women. But because of the high level of deactivation and pre-destination in the system (albumin, SHBG, 3bHSD, aromatase) quite a lot of it, if not all simply never reaches the androgen receptor where it would cause anabolic effects, but also side-effects. So its relatively safe. Doses between 25 and 250 mg per day are used with no adverse effects. 50 mg per day is usually sufficient to be effective in each of the four cases we mentioned up above, so going higher really isn't necessary. Unlike what some suggest or believe, its not advised that Proviron be used when not used in conjunction with another steroid, as it too is quite suppressive of natural testosterone, leading to all sorts of future complications upon discontinuation. Ranging from loss of libido or erectile dysfunction all the way up to infertility. One would not be aware of such dangers because Proviron fulfills most of the functions of normal levels of testosterone.


    Stacking and Use:


    Mesterolone is an oral alkylated steroid. If used primarily as an anti-aromatase drug, using it throughout a longer cycle (10-12 weeks) of injectables may elevate liver values a little bit, though much, much less than one would expect with a 17-alpha-alkylated steroid. Eventhough instead of inhibiting gains, mesterolone may actually contribute to gains. So that's a bit of a shame. Its not quite as toxic since its not alkylated in the same fashion, but at the 1 position, which reduces hepatic breakdown, but not like 17-alpha alkylation. The reason for the change of position I assume, is because alkylating at the 17-alpha position has been shown to reduce affinity for sex hormone binding proteins. This would in turn decrease its ability to free testosterone. Nonetheless the delivery rate is quite good. Its taken daily in 50-100 mg doses.


    The best thing to stack it with is testosterone of course. Its most easily bound to SHBG and albumin, and deactivated for up to 98%. Since the DHT can compete for these structures with higher affinity it would naturally lead to a higher yield of whatever testosterone product you stacked it with. Since DHT levels are notably higher now there is also more stimulation of the androgen receptor causing more strength gains, and because of its affinity for aromatase the overall estrogen level decreases as well. This has as a result that gains are leaner, and once again the overall testosterone yield is increased as less I converted at the aromatase enzyme.


    It's of course used in other stacks with products such as methandrostenolone, boldenone and nandrolone to reduce estrogenic activity and increase muscle hardness. The addition of proviron makes boldenone a dead lock for a cutting stack and for some may even make it possible to use nandrolone while cutting, although the use of Winstrol or a receptor antagonist in conjunction is wishful as well. The benefit of adding it to a nandrolone stack is that it may also help you reduce the decrease in libido suffered from nandrolone, since the latter is mostly deactivated by 5-alpha reductase, an enzyme that makes other hormones more androgenic.


    Proviron is an anti-aromatase, so obviously anti-estrogens would not be needed. Blood pressure medication for those prone to hypertension may be wise, as this DHT can increase the blood pressure.




    Brands & Products:


    Schering Proviron (TK) 10 mg tabs
    Proviron (G, A, B, CH, ES, FR, GB, GR, PL, NL, CZ, TK, Mexico, Dom. Rep., Panama, Guatemala, El Salvador, Honduras, Paraguay, Costa Rica, Nicaragua; Uruguay; Alkaloid YU) 25 mg tabs
    Mestoranum (DK, S, NO) 25 mg tabs
    Proviron (Italy) 50 mg tabs
    Leiras Proviron (F1) 10 or 20 mg tabs
    Asche Pluriviron (G) 25 mg tabs
    Jenapharm Vistimon (G) 25 mg tabs
    Thanks Mountain_Man, pgb thanked for this post
     

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    Great thread
     

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    Default Proviron and Trenbolone (The benefits)

    Proviron, Stacking and Use:
    (Just a refresher as I posted this once before, just in case some noobs missed this)

    Proviron and Trenbolone (The benefits)


    So, the discussion has came about many times over in regards to depression,aggression and/or anxiety,or other sides when on cycle/blast when utilizing Trenbolone, or at times other compounds!
    Let's discuses Tren and one compound that can help assist with side effects that can be unbearable for most,especially anxiety..So lets talk about this shall we?
    Please allow me to illustrate one of shrouded and seldom discussed Drugs in the whole anabolic circuit, with one of themost underrated/pronounced effects ever, that somehow has failed to be discussed upon the masses...

    "Proviron" Mesterolone


    Most of you that have ever took the breakfast of champions "Methandrostenolone", That's right, I'm talking about Dbol. What's the most apparent and conspicuous effects that takes place while taking Dbol? If you were about to say the "sense of well-being" than your correct. One of the most profound and desirable effects that we can have during a cycle..Now, how about after a cycle? Or for longer duration's? But we all know that many of us practice moderation with harsh orals,or I would hope,But, have no concerns with elevated toxicity here!
    One of the greatest characteristics about Proviron that has been shrouded and seldomly discussed is it's "Antidepressant" properties. With this being said, when it was first developed it was widely utilized in treatments for Bi-polar,OCD and Anxiety. As we know that depression is basically a chemical imbalance that comes about through the "Signaling" issues between receptors. Proviron improves the quality of the "channels" that the cells use to communicate and interact. Thus, a similar effect with Dbol where it drastically improves the sense of well being in users. Much like Antidepressants,SSRI (Selective serotonin re-uptake inhibitor, and/or,SNRI (Serotonin-nor-epinephrinere-uptake inhibitor)
    What I'm about to share is a double blind study that clearly shows undoubtedly astonishing results in the patients! An other great reason to consider this compound.
    Why proviron is underestimated, the world may never know

    Tren is the compound that's well known for having a love hate relationship with most users. Most will deem it a necessary evil. But, in fact it doesn't have to be classified as evil after all.https://www.puritysourcelabs.com/inje...mlvial-ep.html
    Allow me to intro some clinical studies that have been conducted with a compound most commonly known as Proviron-trade name (Mesterolone).This agent posses some amazing characteristics with Antidepressant properties, as well Anti-anxiety.
    It works by also metabolizing and being recognized through the endocrine as (other) a neurosteroid,effectively functioning as a so-called proneurosteroid (testosterone is also recognized as one).. These steroids synthesized in the brain (Proviron especially) and have effects on brain function,In addition to their actions on neuronal membrane receptors,improving the quality of the channels that cells use to communicate and interact.

    Proviron/or Masteron and Tren (Masteron can be utilized due to it's targeting similarities)
    Proviron(mesterolone) will exert inhibitory actions on neurotransmission,
    acting as potent positive allosteric modulator of the GABA receptor (This is crucial concerning Tren-Insomnia as healthly function levels ofGABA will produce a stable sleep state/environment for rest) and possess, in no particular order, antidepressant,stress-reducing, feeling warm/fuzzy/rewarding,pro-social, anti-aggressive(huge consider tren sides),pro-sexual,sedative/pro-sleep,cognitive-memory improvement..The list goes on!

    (Where does this apply with Tren? It can aid all the way around with individuals how are sensitive or not.From the social aspect,overwhelming sense of anxiety,lack of sleep,basically everything stated above that may apply with the usage of tren and the onset of its unwanted side)

    In addition to this information, an individual can also utilized masteron (Drostanolonein) in conjunction with Proviron, running both concurrent may yield a great synergenic effect,each compound will compliment one an other. Also the -
    Further more Proviron is a DHT derivative. DHT compounds assist with hardening of the physique, lack of water retention,increased sex drive..Hardening of the physique and lack of water retention go hand in hand. Proviron assists with this, The body recognizes proviron as a DHT,This causes a direct hardening affect on the muscle tissue(Like mast posses,but mast is much more stronger IMO)The increase in hardness comes from a reduction in free estrogen levels, because proviron has the ability to 'latch-on' to the estrogen binding enzymes,It competes so to speak for its position,it does this aggressively, thus decreasing water retention. Also the the lack of aromatization and the fact that the drug is prototypical androgen, causes a significant shift in the body’s estrogen/testosteroneratio.As proviron's atomic structure it is incapable of forming estrogen. It also has properties with AR's.. Increasing the AR expression, proviron/DHT uptake to further increase AR expression, repeating this process over and over ...
    This allows other AAS compounds to appear to be amplified with there effects,assisting the compounds -(What does this mean?)
    It can be a master key so to speak, having multiple functions - It binds aggressively to the AR's and SHBG, thus it can/may increase the activity of other STEROIDS in the system) - This is an added bonus!

    Learn more about Proviron here -

    Functions concerning
    the neurotransmitter/receptor and how it works:
    Below is a image illustrating the neurotransmitter/receptor and how it functions, also I will include some real actual studies conducted with proven results expressing the benefits of this compound (proviron)
    Keep in mind that these doses may seem extreme,its been proven time and time again that such significant dosages are not needed to yield the effect. Merely a daily intake of 50-100 will suffice for almost anyone!



    Citation
    Database: PsycINFO
    [ Journal Article ]
    A comparison of the antidepressant effects of a synthetic androgen (mesterolone) and amitriptyline in depressed men.
    Vogel, William; Klaiber, Edward L.; Broverman, Donald M.
    Journal of Clinical Psychiatry, Vol 46(1), Jan 1985, 6-8.

    Abstract



    1. 26 depressed male outpatients were randomly assigned to 14 wks of treatment with either mesterolone or amitriptyline in a double-blind parallel treatment design. Ss completed the Hamilton Rating Scale for Depression and a symptom checklist each week. Findings reveal that the drugs were equally effective in reducing depressive symptoms. Mesterolone produced significantly fewer adverse side effects than amitriptyline and did not produce hypomania or tachycardia, recognized side effects of amitriptyline. (10 ref) (PsycINFO Database Record (c) 2013 APA, all rights reserved)



    Methods Find Exp Clin Pharmacol. 1984 Jun;6(6):331-7.
    The effects of mesterolone, a male sex hormone in depressed patients (a double blind controlled study).
    Itil TM, Michael ST, Shapiro DM, Itil KZ.
    Abstract
    Based on computer EEG (CEEG) profiles, in high doses, antidepressant properties of mesterolone, a synthetic androgen, were predicted. In a double-blind placebo controlled study, the clinical effects of 300-450 mg daily mesterolone were investigated in 52 relatively young (age range 26-53 years, mean 42.7 years) male depressed outpatients. During 6 weeks of mesterolone treatment, there was a significant improvement of depressive symptomatology. However, since an improvement was also established during the placebo treatment, no statistically appreciable difference in the therapeutic effects of mesterolone was established compared to placebo. Mesterolone treatment significantly decreased both plasma testosterone and protein bound testosterone levels. Patients with high testosterone levels prior to treatment seem to have had more benefit from mesterolone treatment than patients with low testosterone levels. The degree of improvement weakly correlated to the decrease of testosterone levels during mesterolone treatment.


    Information confirming no HTPA shutdown/suppression during PCT

    These are some research articles that may justify the use of low/moderate dose Proviron during PCT:
    --------------------------------------------------------------------------------------------
    AAKVAAG, A., and S. B. STROMME. "The effect of mesterolone administration to normal men on the pituitary-testicular function."Acta endocrinologica77.2 (1974): 380-386.

    ABSTRACT
    Mesterolone (1α-methyl-5α-dihydrotestosterone) has been given to 10 normal men, age 24–27 years, and the effect on the plasma levels of ICSH, FSH and testosterone has been studied.No effect on the plasma levels of ICSH and FSH could be detected. After 4 weeks on 75 mg mesterolone per day a significant (P < 0.01) drop in the mean value for plasma testosterone level was observed, 5.2 to 4.0 ng/ml. After another 4 weeks on 150 mg mesterolone per day a further decrease to 3.5 ng/ml was found.During mesterolone administration the protein binding of testosterone in plasma was significantly reduced, and it appeared that the level of free (non-protein bound) testosterone in diluted plasma remained unchanged, 0.37 and 0.41 ng/ml, before and after mesterolone administration respectively.The results suggest thatmesterolone given in doses of 75 and 150 mg/day to normal men does not suppress the pituitary ICSH production or the testicular testosterone production

    --------------------------------------------------------------------------------------------

    GORDON, R.D., THOMAS, M.J., POYNTING, J.M. and STOCKS, A.E. (1975), Effect of Mesterolone on Plasma L.H., F.S.H. and Testosterone. Andrologia, 7: 287–296. doi: 10.1111/j.1439-0272.1975.tb00942.x
    Summary
    It has been claimed that orally administered mesterolone, unlike l7a-methyl testo- sterone, does not suppress endogenous gonadotrophins and testesterone. To investi- gate this, both drugs were administered, in turn, to four normal men and plasma te- stosterone, L.H. and F.S.H. were measured serially. Mesterolone administration was associated in all four subjects with significant and similar falls in plasma testosterone, but significant suppression of gonadotrophins took place in only two of them. Any changes which occured were apparent by the end of the first week of therapy. Administration of half the dose of 17a-methyl testosterone to the same four subjects caused significant suppression of testosterone in each and suppression of one or both gonadotrophins in each.
    In longer term studies in patients (5-30 months) involving serial measurements at intervals of one to two months, there was evidence of significant suppression of L.H. and F.S.H. by 17a-methyl testosterone, but not by mesterolone, which was clinically a less effective androgen.
    --------------------------------------------------------------------------------------------

    WANG, C., BURGER, H.G., de KRETSER, D.M., DULMANIS, A., HUDSON, B., KEOGH, E.J. and SUTHERS, M.B. (1974), Effect of Mesterolone on Serum FSH, LH and Plasma Testosterone in Normal Men. Andrologia, 6: 111–117. doi: 10.1111/j.1439-0272.1974.tb01604.x

    Summary

    To determine whether the claim that mesterolone, an orally active androgen, does not cause suppression of gonadotrophin secretion, two groups of five normal men were treated with 100 and 200 mg. daily respectively for 7 days. Serial measurements of serum FSH, LH and plasma testosterone were made on samples taken at 15 minute intervals over 2 hr both before and during treatment. Modest falls in FSH, LH and testosterone levels were observed in both groups, the percentage suppression being 21% and 18% for FSH, 19% and 15% for LH and 9% and 8% for testosterone at the lower and higher dosage levels respectively.
    --------------------------------------------------------------------------------------------

    200mg is a far greater dose than I would deploy during PCT (50mgs is ideal). From these studies and other articles we see have read, it's clear that there is almost minimal/no influence on the HTPA, any effect would be absolute minimal and negated by other appropriate compounds used during that period (HCG, Aromasin, Nolvadex and HGH)...

    Team PSL supervisor
    Vision


    PRESCRIBING INFORMATION

    PROVIRON
    Tablets


    COMPOSITION
    Each tablet contains 25 mg mesterolone.

    ACTION
    -dihydro-testosterone, which is α-methyl compound of 5αMesterolone is the 1
    considered to be the proper active androgen in many androgen-dependent target
    organs.

    Proviron is an oral androgen preparation which has only a slight central inhibitory
    effect and, consequently, no restrictive effect on testicular function.

    Proviron balances a deficiency of androgen formation which begins to fall gradually
    with increasing age. Therefore, Proviron is suitable for the treatment of all conditions
    caused by deficient endogenous androgen formation. In the recommended therapeutic
    dosage, Proviron will not impair spermatogenesis. Proviron is especially well
    tolerated by the liver.

    PHARMACOKINETICS AND METABOLISM

    Following oral ingestion mesterolome is rapidly and almost completely absorbed in a
    wide dose range of 10 - 100 mg. The intake of Proviron generates maximum serum
    drug levels of 3.1 1.1 mg/ml after 1.6 0.2 hours. Thereafter drug levels in serum
    decrease with a terminal half-life of 12 13 hours. Mestorelone is bound to serum
    proteins by 98%. Binding to albumin accounts for 40% and binding to SHBG to 58%.

    Mestorelone is rapidly inactivated by metabolism. The metabolic clearance rate from
    serum accounts for 4.4 1.6 ml. min −1.kg−1 .
    There is no renal excretion of unchanged drug. The main metabolite has been
    identified as 1α - methyl-androsterone, which - in conjugated form - accounts for 55 -
    70% of renally excreted metabolites. The ratio of main metabolite glucoronide to
    sulphate was about 12:1. As a further metabolite 1α - methyl- 5α androstane-3α, 17β-
    diol has been recognized, which accounted for about 3% of renally eliminated
    metabolites. No metabolic conversion into estrogens or corticoids has been observed.
    In form of metabolites mesterolone is excreted by about 85% of dose with the urine
    and by about 14% of dose with the faeces. Within 7 days 93% of dose have been
    recovered in excreta, the half of which had been excreted within 24 hours.

    The absolute bioavailability of mesterolone was determined to about 3% of the oral
    dose.
    The daily intake of Proviron will lead to an about 30% increase in drug serum levels.
    INDICATIONS

    Androgen therapy in male patients only.

    Reduced efficiency in middle and advanced age •

    Complaints attributable to androgen-deficiency, such as reduced efficiency,
    easy fatigability, lack of concentration, weak memory, disturbances of libido and
    potency, irritability, disturbances of sleep, depressive moods, and general vegetative
    complaints, can be overcome or improved by the use of Proviron tablets.

    Potency disturbances •

    Potency disorders based on an androgen deficiency are eliminated by
    administration of Proviron. If other factors are the sole cause or if they contribute to
    the disorders, Proviron may be administered in support of other therapeutic measures.

    Hypogonadism •

    Growth, development and function of androgen-dependent target organs are
    stimulated by Proviron. It promotes development of secondary male sex
    characteristics in cases of prepuberal androgen-deficiency.

    Proviron eliminates deficiency symptoms in cases where a loss of gonadal
    function has occurred postpuberally.

    Infertility •

    Oligozoospermia and deficient Leydig-cell secretion may be the cause of
    infertility. With Proviron, sperm count and sperm quality as well as the fructose
    concentration in the ejaculate can be improved or normalized, thus increasing the
    chances of procreation.

    CONTRAINDICATIONS
    Prostatic carcinoma.

    Previous or existing liver tumours.

    WARNINGS
    Androgens are not suitable for enhancing muscular development in healthy
    individuals or for increasing physical ability.

    Risk of carcinoma •

    The occasionally expressed fear that prostatic carcinoma can be induced by
    the use of androgens is unfounded. Androgens have no carcinogenic action.

    Observations made over many years have shown that the risk of carcinoma in
    men treated with androgens was no greater than in an untreated control group.
    Specific studies of male patients under long-term and high-dosed therapy with

    testosterone produced no signs of prostatic carcinoma and, hence, no evidence that the
    exogenous supply of testosterone activates any atypical cells which may be present.

    The regular check-ups during the therapy failed to reveal a single case of
    carcinoma among patients with prostatic adenoma, whose complaints were favourably
    influenced by Proviron.

    Since androgens can exacerbate a clinically manifest carcinoma of the
    prostate, malignant tumours of the prostate must be ruled out before the start of
    Proviron treatment. As in prophylactic examinations of men, regular rectal and - if
    required to confirm the diagnosis - biopsy examinations must be carried out during
    the therapy.

    Liver tumours •

    In rare cases, benign, and in even rarer cases, malignant liver tumours leading
    in isolated cases to life-threatening intra-abdominal haemorrhage have been observed
    after the use of hormonal substances such as the one contained in Proviron. A liver
    tumour should be included in the differential-diagnostic considerations if severe upper
    abdominal complaints, a liver enlargement or signs of an intra-abdominal
    haemorrhage occur. If necessary, the preparation must be withdrawn.

    ADVERSE REACTIONS
    Proviron is well tolerated even as regards liver function. Laboratory tests conducted
    during high-dosed and long-term treatment produced no evidence for an injurious
    effect. If, in individual cases, frequent or persistent erections occur, the dose should
    be reduced or the treatment discontinued in order to avoid injury to the penis.

    DRUG INTERACTIONS
    None recorded so far.

    DOSAGE AND ADMINISTRATION
    The tablets should be swallowed whole with some liquid.

    The following dosages are recommended:

    Reduced efficiency and potency disturbances: •

    Commencement of treatment:

    1 Proviron tablet 3 times per day.

    After satisfactory clinical improvement, it can be tried to reduce the dose.

    Continuation of treatment:

    1 Proviron tablet twice or once per day
    According to the type and severity of the complaints, the dose for further
    treatment is to be adjusted to individual requirements. Continuous treatment
    over a period of several months is recommended.

    Hypogonadism requires continuous therapy: •

    For development of secondary male sex characteristics, 1 - 2 Proviron tablets
    3 times per day for several months.

    As maintenance dose, 1 Proviron tablet 2 - 3 times per day will often be
    sufficient.

    Infertility - for the improvement of sperm quantity and quality: •

    1 Proviron tablet 2 - 3 times per day for a cycle of spermatogenesis, i.e. for
    about 90 days. If necessary, Proviron treatment is to be repeated after an
    interval of several weeks.

    To achieve a higher fructose concentration in the ejaculate in cases of
    postpuberal Leydig-cell insufficiency: 1 Proviron tablet twice per day over
    several months.

    OVERDOSAGE
    Acute toxicity studies using single administration showed that Proviron is to be
    classified as practically non-toxic. No risk of toxicity is to be expected even after
    inadvertent single administration of a multiple of the dose required for therapy.

    PRESENTATION
    Bottles of 20 and 50 tablets.

    REFERENCE
    Update product information.

    MANUFACTURER
    Schering AG, Berlin, Germany.

    IMPORTER
    Agis Commercial Agencies (1989) Ltd., Bnei-Brak.

    15.11.95
    Last edited by Presser; 06-12-2018 at 12:54 PM.
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    This read has me wanting to give it a run
     

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    Anything that will help with tren sides would be a great addition.
     

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    Quote Originally Posted by yellow snow View Post
    Anything that will help with tren sides would be a great addition.
    Provolone helps tren sides? What sides?
     

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    Quote Originally Posted by jolt View Post
    Provolone helps tren sides? What sides?
    because "PROVOLONE" makes sandwiches rock... I love me some provolone cheese, especially when tren has me in a mood....
    Likes jolt, Zao liked this post
     

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    Quote Originally Posted by Vision View Post
    because "PROVOLONE" makes sandwiches rock... I love me some provolone cheese, especially when tren has me in a mood....
    Provirone,I hate spell check.
     

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    Quote Originally Posted by jolt View Post
    Provirone,I hate spell check.
    I was joshing ya homie.

    listen... proviron helps improve the neurochatter and improves the pathways assisting with stable brain functions/secretions!

    this compound.
    Why proviron is underestimated, the world may never know

    Tren is the compound that's well known for having a love hate relationship with most users. Most will deem it a necessary evil. But, in fact it doesn't have to be classified as evil after all
    Allow me to intro some clinical studies that have been conducted with a compound most commonly known as Proviron-trade name (Mesterolone).This agent posses some amazing characteristics with Antidepressant properties, as well Anti-anxiety.
    It works by also metabolizing and being recognized through the endocrine as (other) a neurosteroid,effectively functioning as a so-called proneurosteroid (testosterone is also recognized as one).. These steroids synthesized in the brain (Proviron especially) and have effects on brain function,In addition to their actions on neuronal membrane receptors,improving the quality of the channels that cells use to communicate and interact.

    Proviron/or Masteron and Tren (Masteron can be utilized due to it's targeting similarities)
    Proviron(mesterolone) will exert inhibitory actions on neurotransmission,
    acting as potent positive allosteric modulator of the GABA receptor (This is crucial concerning Tren-Insomnia as healthly function levels ofGABA will produce a stable sleep state/environment for rest) and possess, in no particular order, antidepressant,stress-reducing, feeling warm/fuzzy/rewarding,pro-social, anti-aggressive(huge consider tren sides),pro-sexual,sedative/pro-sleep,cognitive-memory improvement..The list goes on!

    Last edited by Presser; 06-12-2018 at 12:55 PM.
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    Proviron is a good add for any cycle or HRT.
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    How toxic is proviron?and how long can you run it?
     

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    Quote Originally Posted by jolt View Post
    How toxic is proviron?and how long can you run it?
    not very toxic-you can run it for a while...I know there are guys here that say they will never run a cycle without it, I never got anything out of it
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    Quote Originally Posted by dorian123 View Post
    not very toxic-you can run it for a while...I know there are guys here that say they will never run a cycle without it, I never got anything out of it
    That sucks since it is pricy.
     

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    provolone lmao
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    FCK spell check lmao.I need the steroid version of it
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    Default Proviron has great qualities

    Quote Originally Posted by jolt View Post
    This read has me wanting to give it a run
    I have been using Gp proviron during my tren ace, dbol, testosterone e ,eq cycle and i have been using it at 50 mg a day.It definately decreases the tren sides such as insomnia and nandralone problems with decreased sex drive.Definately a great addition to any cycle.But you must be using testosterone with these cycles
     

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    Love that cheese. LOL
    Get It Done!

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    I never make a sandwich without it


    Team MeccaGear!
     

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    Proviron dosages and cycle stacking for maximum mass muscle gains. Yeah a little SEO gibberish there. lol. But a great Thread of information now that i deleted all the PSL BS out
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    Great info.
    Get It Done!

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