Follistatin? question

If follistatin were injected, would it offer any benifits as to blocking the myostatin, production. Are any bodybuilders into doing this, or is this an altogether inefficent approch to gaining muscle size?




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WoW, amazing what the internet can do....... i can't belive i found this shit.

Is anyone familar with how to inject the myostatin antibody?


how much to take, take cycle informtaion........

anyone have any experiance with it?.... anything like that,

ie. anyone try it on their arrmadilo, groundhogg..., pot bellyed pig ?

So im niot sure what this is, does it turn of the myostatin gene or downregulate it or something, im not sure rrealy, i been reading a shit load about this stuf but i cant make heads or tails of it bro, but im very interested in hearing about it in lamens terms

yeh man, i have studied it as well and it is very confusing.

It is so confusing to people because they do not specify when they are talking about an in vivo application as apposed to in vitro.

and there really isn't a great deal of in-depth information on it because companies like metamorphix are so damn discrete about it.

In vivo meaning the mouse was genetically tampered with in embrio form to produce an freakishly abnormal amount of follistatin. Follistatin does many things in the body, but the one were interested in , downregulateing myostatin (it binds to it and negates it so it cant attach to the receptor cells), well these mice constantly produce a high level of the myostatin negating follistatin.

There are other cases where in vivo, the mouse has the myostatin gene deleted but its the same result as having the myostatin gene and having a shitload of follistatin.

Now this case of course in vivo would be useless to us, but there are other cases in vitro where apparently like (igf-1, and other relatively new compounds) they have recently made a recombant follistatin. They inject follistatin into the mice and apparently it downregulates the myostatin. So when you would get off of it you should keep the gained muscle from the cycle but additional proliferation would stop occurring. So i guess you could just stay on it until you got as big as you wanted, or got injured by tearing something because so much muscle is built up. While your on the follistatin the myostatin from the myostatin gene is blocked, so new myo blast cells can proliferate and new muscle cells grow.

I have consequently found follistatin, and other things that i did not think were available on the internet and im sure if you do an in depth search you will as well.

What i don't know is, how much to inject, what your cycle would be, and all the real stuff you would need to know to actually use the stuff, but im sure as time goes along i will find people and people will come forward with that information......

but yeh sorry bro i know no real, useful information about how to use or how much to take but i simply know this product is now out there and in some peoples bodybuilding arsenals!

im sure well find people bro........

just keep searchin......and reading...... ill prvate mail you if i find anything good.

i seen 1mg for $3,800 that seems steep

It sure does seem steep bro, but if it does what its supposed to ….permanent new muscle with no real increased risk for cancer, permanent strength increase, all of skellital muscle and it's not supposed to affect orgins or heart, than it is a pretty impressive compound in my opinion ...

hey man i would by it if i had the money.....man it will be great when i get out of college and have a real job ill probably spend 90% of my money on research! hahahah

This should be added to Lab-Corp.

I am thinking about......... $900 per ml. hehe

Skip

yeah i wonder how much they would sell at those prices,lol, souncs interesting though and i'd bet there are some people out there who have tryed it, no doubt

bump

definitely an interesting substance I will be reading about

Presser said:

yeah i wonder how much they would sell at those prices,lol, souncs interesting though and i'd bet there are some people out there who have tryed it, no doubt

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you wanna know the truth

you can't handle the truth

he,he

I can chime in on the molecular side of things...Follistatin is just one of the proteins that binds to and inhibits myostatin; it works with growth and differentiation factor-associated serum protein-1 (GASP-1) and a follistatin-related gene in the complex; they all have to be chopped apart in order for myostatin to exert its inhibitory action. Unfortunately no one is sure how the complex gets chopped apart (or how to prevent it from getting chopped up). Having excess follistatin around (or GASP) will bind more myostatin and could decrease its action; the easier approach seems to be injecting the antibody to myostatin. In rats that were injected with the antibody their grip strength increases and side effects during the study were minimal (organ size remained the same and bloodwork looked good). The injections were given IP and all muscles they looked at increased in 2-4 weeks. How do you get some? The antibody was made up in MA, should be commercially available soon ;-).

Type up myostatin antibodys on your search engine and you should get at least two lab companies that will sell it to you. I don't remember the price but price is of little use untill some willing lab rat tells us how much and how often we need to take it.

Personaly I have a pygmi albino tortoise that could use some experimenting on if some one wants to pony up the meds.

lmao at ATK's pygmi albino tortoise