Get_Swole
MuscleChemistry Registered Member
This is the summary from the masters thesis from a student from Baylor which does a LOT of creatine research. I'm sure the full research will be published in journals soon. I with others have been saying for a long time that CEE has no benefit over creatine monohydrate and that it's a marketing rip.
BEHOLD!!!!!
Now i'm sure alot of the BROSCIENCE hippies will come in here and tell me "but bro I FEEL something on CEE"
yup... you are feeling the creatinine exiting your kidneys chief.
ABSTRACT
The Effects of Creatine Ethyl Ester Supplementation Combined with Resistance Training
on Body Composition, Muscle Mass and Performance, and Intramuscular Creatine
Uptake in Males
Mike Spillane, M.S.Ed.
Advisor: Darryn S. Willoughby, Ph.D.
Creatine monohydrate has become one of the most popular ingested nutritional supplements due to its potential enhancement of athletic performance. Creatine absorption from the serum into skeletal muscle occurs through the utilization of a membrane-spanning protein, CreaT1. Numerous creatine formulations have been developed primarily to maximize creatine absorption. Creatine ethyl ester (CEE) has been chemically modified by adding an ester group and is thought to increase creatine bioavailability by by-passing the CreaT1. This study examined how a seven week supplementation regimen with CEE affected body composition, muscle mass and performance, whole body creatine retention, as well physiological and molecular adaptations, associated with creatine uptake in nonresistance-trained males following a resistance-training program. Results demonstrated that CEE did not show any additional
benefit to increases in muscle strength/performance or a significant increase in total muscle creatine when compared to creatine monohydrate or placebo. CEE supplementation did show a large increase in creatinine levels throughout the study.
discuss.....
BEHOLD!!!!!
Now i'm sure alot of the BROSCIENCE hippies will come in here and tell me "but bro I FEEL something on CEE"
yup... you are feeling the creatinine exiting your kidneys chief.
ABSTRACT
The Effects of Creatine Ethyl Ester Supplementation Combined with Resistance Training
on Body Composition, Muscle Mass and Performance, and Intramuscular Creatine
Uptake in Males
Mike Spillane, M.S.Ed.
Advisor: Darryn S. Willoughby, Ph.D.
Creatine monohydrate has become one of the most popular ingested nutritional supplements due to its potential enhancement of athletic performance. Creatine absorption from the serum into skeletal muscle occurs through the utilization of a membrane-spanning protein, CreaT1. Numerous creatine formulations have been developed primarily to maximize creatine absorption. Creatine ethyl ester (CEE) has been chemically modified by adding an ester group and is thought to increase creatine bioavailability by by-passing the CreaT1. This study examined how a seven week supplementation regimen with CEE affected body composition, muscle mass and performance, whole body creatine retention, as well physiological and molecular adaptations, associated with creatine uptake in nonresistance-trained males following a resistance-training program. Results demonstrated that CEE did not show any additional
benefit to increases in muscle strength/performance or a significant increase in total muscle creatine when compared to creatine monohydrate or placebo. CEE supplementation did show a large increase in creatinine levels throughout the study.
discuss.....
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