Questions for injectable B12 users.

Jozifp103

Jozifp103

MuscleChemistry Registered Member
Thinking about running some injectable B12, but have a few questions that my research hasn't answered so well. There seems to be conflicting info so I'll just seek out some first hand experience.


1.) Mythylcobolamine vs. Cyanocobalamine. Supposedly cyano has to be broken down to methyl before it can be used, and ends up losing a lot of potency in the process, making methyl far superior. However, methyl is far more expensive....worth the price difference?


2.) Do you have to up the dose if using cyano since it is not absorbed as efficiently as methyl?


3.) What dosing schedule worked best for you, and was it subQ or IM?


Thanks all!
 
Most use cyanocobalamin because it is the least painful. Here's some info on the different types:

From the blog of Fred Bloem, MD, – Holistic Physician in Maryland:


Cyanocobalamin can be given as an intramuscular injection. It should not be given intravenously. However, after injection it will need to convert to methylcobalamin, and then to hydroxocobalamin to be used by the body. Of all the forms of Vitamin B12 it is the least painful for the patient to inject. After introduction into the body it provides a small amount of cyanide. For individuals who are overall very healthy this is a good choice and this is also the least expensive form of injectable Vitamin B12. It is known that some people, such as smokers, are less able to transform cyanocobalamin into methylcobalamin due to toxins and heavy metals in the liver. These individuals need to use other forms of Vitamin B12.


Methylcobalamin is more bioactive and can be given intramuscularly, intravenously, and intraarticularly. It is slightly painful to inject into the muscle. In my practice I also use methylcobalamin when I do Prolozone injections into joints and into subcutaneously (under the skin). This is also a better choice for smokers who are unable to convert cyanocobalamin into methylcobalamin.


Hydroxocobalamin is the most bioactive form of Vitamin B12 and mostly given intravenously as intramuscular injections are very painful. If given intramuscularly it is mixed the local anesthetic procaine. Hydroxocobalamin is retained longer in the body and can be dosed less frequently. An additional application of hydroxocobalamin is that it can be used for patients with cyanide poisoning as it binds cyanide and allows for elimination through the kidneys.

 
And to answer the question:

1) I've only used cyanocobalamin (it's the cheapest of course)

2) The maximum I've used for dosage is 2ml. Did 2ml for first few days, then maintained with 1ml.

3) Took every day at 1ml after the initial loading of 2ml for first few days, almost 3 weeks was how long the vial lasted (had a 30-40ml bottle).
 
cyanocobalamin is all I ever used 1000 mcg Ed sub-q no pain for me felt great and full of energy the entire time I use it I get get grade it works fine and super cheap
 
same here used the same b12 injection.not sure i noticed much but continued to use a couple bottles worth.cant say for sure if it helped with energy or not.iwas a little disapointed cause i thought i would be more energized.i injected in my delt each time
 
gandhisays said:
same here used the same b12 injection.not sure i noticed much but continued to use a couple bottles worth.cant say for sure if it helped with energy or not.iwas a little disapointed cause i thought i would be more energized.i injected in my delt each time
Click to expand...

Same here, won't be buying again.
 
​Thanks guys. I expected mixed reviews...as I do with any supplement or drug. Looks like I'll just have to try it out myself!
 
I kept meaning to register, but finally did so to reply to this. I use a bunch of other injectables besides AAS, like curcumin, glutathione, B complex, etc.

My wife enjoys the results of my test usage, but generally thinks it's weird how many different shots I take.

However, one morning I was loading up some B complex into a slin and she asked about it. Apparently the topic of B12 shots came up at her work, and her coworker was paying $20 to go in and have a single shot administered.

Anyways, long story short, she asked to try it, and it made a huge difference in her energy levels. Everyone's different. She now asks me to load up a slin pin for her several times a week, and she subq's it.
 
Jozifp103 I will say try it b-12 does work for most people it's a great add on during cycle and post cycle it helps my wellbeing and my energy levels I feel more alert when I am on been using it off and on for 15 years it dose help u just have to find the right amount for u brother. Give it a try it's cheape so u don't lose anything like I said above I use sub q Ed 1000 mcg but everyone is different my freind good luck hope u find the sweet spot
 
jcc80 said:
I kept meaning to register, but finally did so to reply to this. I use a bunch of other injectables besides AAS, like curcumin, glutathione, B complex, etc.

My wife enjoys the results of my test usage, but generally thinks it's weird how many different shots I take.

However, one morning I was loading up some B complex into a slin and she asked about it. Apparently the topic of B12 shots came up at her work, and her coworker was paying $20 to go in and have a single shot administered.

Anyways, long story short, she asked to try it, and it made a huge difference in her energy levels. Everyone's different. She now asks me to load up a slin pin for her several times a week, and she subq's it.
Click to expand...

Welcome to MuscleChemistry brutha! Your wife sounds like a cool lady! lol
 
Thanks man. Actually she's been largely indifferent to the stuff I do, and it was only a couple weeks ago that she took the plunge.

What really surprised me is she let me put a half ml of curcumin in her shoulder when she was sick. And curcumin can be painful.
 
well indifferent aint as good as supportive but a whole hell of a lot better then condemning lol.
 
yellow snow said:
I guess I should have clarified this. Not oil soluble, but is the b12 suspended in an oil ester or water (test E vs winstrol depot)
Click to expand...
Gotcha. I haven't seen a suspension. I get mine from Animal's board, but I suspect it's easily obtained from veterinary supply sites.
 
jcc80 said:
Gotcha. I haven't seen a suspension. I get mine from Animal's board, but I suspect it's easily obtained from veterinary supply sites.
Click to expand...
Reason i ask is I got a suspension from India and I am wondering if that is why I don't get much from it. My doc originally prescribed it in an oil based form.
 
I use Hydroxocobalamin, body seems to absorb most of it, I never pee red after administering it, however I would also pee red with cyanocobalamin. PIP with with Hydro is also non existent. Not that cyano was any bad in any way, but I could still feel it a little.
 
You must log in or register to reply here.

Similar threads

Muscle Insider
How to Inject Testosterone – TRT and Bodybuilding
Replies
0
Views
97
Muscle Insider
Muscle Insider
yourmuscleshop
CYANOCOBALAMIN – VITAMIN B12
Replies
1
Views
256
PEP PATRIOT52
PEP PATRIOT52
Muscle Insider
The Morning Dose 15: The FDA is After Our Peptides Again?
Replies
0
Views
132
Muscle Insider
Muscle Insider
Muscle Insider
The Morning Dose #32: Nootropic Peptides, Protein Dosing, and the Twin Study
Replies
0
Views
53
Muscle Insider
Muscle Insider
Presser
Trenbolone vs Parabolan
Replies
0
Views
135
Presser
Presser
Back
Top