Liver Support Especially Important for A Steroid Cycle

Iron Game

Iron Game

Veteran
Even with a healthy diverse diet containing a variety of nutritious foods, it is difficult to obtain all the vital nutrients your body needs to function at its maximum capability. Taking supplements allows individuals to harvest the benefits of a diet filled with vitamins, minerals and protective anti-oxidants essential to overall good health. There is no substitute for eating a well balanced diet containing whole grains, green leafy vegetables, and lean proteins; but to couple that with premium supplements you have now significantly increased your general health potential.

Today’s world is filled with toxic environments that unknowingly wreak havoc on our internal organ systems. Even with an individual that does not partake in alcohol consumption, cigarette smoking or drug use, toxin and free-radical exposure cannot be avoided. Our liver cells work overtime detoxifying and removing these harmful substances from our bodies. Supplements that help protect and regenerate the liver carry enormous health benefits for every individual to gain from.

Silymarin, is a substance from the seeds of the milk thistle plant and has shown to have many liver protective qualities. It decreases liver inflammation and guards liver cells against the destructive effects of pollutants that we are exposed to on a daily basis. A powerful anti-oxidant used in Europe for thousands of years to treat liver and gallbladder diseases, it can be taken as a preventative measure to help fend off the unseen assault on such a vital organ necessary for overall health.

Gabriel Wade, M.D.
 
I most definitely swear by TUDCA or UDCA, whichever you can get your hands on. If your doc will prescribe you some UDCA, take advantage of it!!!
 
Great post. Silymarin is a good year round supplement. LIV-52 is another good year round liver supplement. TUDCA is great especially when your liver is being stressed by oral aas. NAC and ALA are other great detoxifiers. But the best liver protector is definitely synthergine by synthetek. I look and feel so much better on synthergine even when running strong orals. It's a good sign when the whites of your eyes are bright white and it does that to me. It's also great for reducing certain side effects from strong orals such as maintaining your appetite. The TUDCA guys should definitely try out synthergine. I use it year round but for guys just wanting to use it with orals I recommend taking LIV-52 for the rest of the year as a cheap option. Staying hydrated especially with warm lemon water is another great body detoxifier.
 
Elvia1023 said:
Great post. Silymarin is a good year round supplement. LIV-52 is another good year round liver supplement. TUDCA is great especially when your liver is being stressed by oral aas. NAC and ALA are other great detoxifiers. But the best liver protector is definitely synthergine by synthetek. I look and feel so much better on synthergine even when running strong orals. It's a good sign when the whites of your eyes are bright white and it does that to me. It's also great for reducing certain side effects from strong orals such as maintaining your appetite. The TUDCA guys should definitely try out synthergine. I use it year round but for guys just wanting to use it with orals I recommend taking LIV-52 for the rest of the year as a cheap option. Staying hydrated especially with warm lemon water is another great body detoxifier.
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Good addition thx
 
Presser said:
warm lemon water doesnt sound so tasty lmao
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It's actually alright but sure cold water tastes nicer. My gf is sick now and wanted me to do tea with honey and lemon. I tried it myself and I am hooked. Not that you need sugar with synthetine but everytime I inject it now I use it as an excuse to have one of those teas. Black tea, 2 tablespoons of honey and some squeezed lemon :)
 
Taking 10caps of Liver support per day due to the 100mg of Anavar. I know it's easy on our bodies but better safe ..
 
cybrsage said:
In clinical studies, TUDCA actually beat out UDCA by a small margin as the better liver support. Go figure, eh?
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very surprised.............goes to show natural is sometime more powerful than pharma. I do like the cost with the udca since it is covered under insurance:thumbsup:
 
cloudstrife1218 said:
could you cite the study please.
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Sure thing, brother! I should have done it at the outset (and usually do).

Abstract

Taurodeoxycholic acid (TUDCA) and ursodeoxycholic acid (UDCA) exert a protective effect in chronic cholestasis. This study reports the effect of TUDCA and UDCA on an in vitro model for ethanol-induced liver damage.
Hep G2 cells were incubated for 24 hours with 80 mmol/L ethanol in the presence or absence of 50 ***956;mol/L TUDCA or UDCA. Cells were also pretreated with 80 mmol/L EtOH and then exposed to 50 ***956;mol/L bile acids. Cytotoxicity was assessed by the metabolism of formazan (3-(4,5-dimethyl-thiazol-2-yl)-2,5-diphenyl tetrazolium bromide and sodium 3,3***8242;-(phenylamino) carbonyl-3,4-tetrazolium-bis (4-methoxy-6-nitro) benzene sulfonic acid hydrase and by the release into the culture medium of different enzymes (aspartate aminotransferase, glutamate dehydrogenase, ***947;-glutamyl transferase, and lactate dehydrogenase).

The incubation of Hep G2 with EtOH significantly (P < 0.001) increased cytotoxicity. Both TUDCA or UDCA reduced cytoxicity to a similar extent (P < 0.001). Cells pretreated with EtOH and then added with TUDCA or UDCA responded differently because TUDCA was significantly more effective (P < 0.05) than an equimolar dose of UDCA in reversing the damage. Electron microscopic examination revealed that TUDCA and UDCA were both able to prevent mitochondrial damage and to reduce steatosis induced by EtOH.

Low doses of TUDCA and UDCA protect Hep G2 cells from EtOH-induced cytotoxicity. However, TUDCA seems to be more effective than UDCA in reversing the damage.
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http://www.gastrojournal.org/articl...er=http://www.bing.com/search?q=tudca+vs+udca

You will have to go down the page a bit to find this stuff.
2.1. Absorption and bioavailability
After oral administration, TUDCA appears to be more effective in raising bile concentrations of UDCA (and downstream effects, such as reducing liver enzyme levels) than UDCA itself; this is most likely due to the Taurine group enhancing bioavailability.[3] [4] The process of conjugating UDCA with taurine is a rate-limiting step, and this rate-limit is avoided with supplementation of TUDCA.[5]

2.2. Distribution
Orally administered TUDCA, at 750mg daily, was able to significantly change the UDCA content of serum, fecal, and urinary bile measurements after 2 months of supplementation; suggesting systemic distribution

Preliminary, but TUDCA appears to be able to protect cells from dysfunction associated with hyperglycemia and may reduce the effects of insulin resistance before they happen (beta-cells) and even therapeutically with the potency of some diabetic pharmaceuticals (in regards to the liver and skeletal muscle)

Might alleviate alcohol's adverse effects on the liver, but appears to be needed to be taken after drinking and may be damaging if taken before
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http://examine.com/supplements/Tauroursodeoxycholic+Acid/
 
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