Muscle mechanic
MuscleChemistry Registered Member
Mk677 oral growth hormone secretagogue
Stimulates hgh and IGF.
Ibutamoren increases growth hormone levels by mimicking the action of the hormone*ghrelin*and binding to one of the ghrelin receptors (GHSR) in the brain. Activated GHSR stimulates growth hormone release from the brain.
GHSR is found in brain regions that control appetite, pleasure, mood, biological rhythms, memory, and cognition. Therefore, we can expect that ibutamoren may also affect these functions. However, so far, clinical studies describe only the effects ibutamoren has on*appetite – and as expected, like ghrelin, ibutamoren increases it.
A great thing about ibutamoren is that it increases growth hormone levels with little or no increase in other hormones, such as cortisol. Cortisol suppresses the immune system, reduces wound healing, and impairs learning and memory, and it’s usually not good to have this hormone elevated.
Optimize your levels and keep them balanced by testing blood levels.
Ibutamoren can increase growth hormone,*IGF-1, and*IGFBP-3*levels in children with growth hormone deficiency. Furthermore, these effects are achieved without changing the concentrations*of prolactin, glucose, triiodothyronine*(T3),*thyroxine*(T4), thyrotropin,* cortisol or insulin.
In severely GH-deficient men, ibutamoren increased IGF-1 and growth hormone, with no significant changes in cortisol, PRL, and thyroid hormone levels. However, insulin and glucose were increased.
After a quick run down of MK677 what are y'all that use it dosing it at??
I have read 25mg too much, makes tired and increases weight with hunger and water retention. And if taken at night that sleeping not as well with often waking up with vivid dreams...
On other hand taking in morning sleep is great at night but lethergy bad in day.
12.5mg mk677 taken in morning seems to be better result for sleep at night and aiding in anti-aging with little to no sides only benifits. Also that this dose or a smaller dose great with 2iu of hgh and increases levels of IGF and hgh thru out alone and with 2iu hgh the spike added to and one can benifit like taking 4iu Hgh with combo.
Or 2iu a day Hgh benifits from 12.5mg dose. I read alot on road so started this off here to see what u guys think before doing a big write up on info, studies, and bros doing bloods on it....
My wife wants to try 12.5mg a day for benifits of anti-aging, fat loss and healing.
I am interested in using it too but with 2-3iu hgh..
I am more than sure that IGF 1 lr3 IM would or could be more of benifit with thoughts of receptors maybe open because liver is manufacturing igf in this period?? Don't know just a thought. I like IGF 1 lr3 with hgh timing igf at hgh peak during workout.
Tell me y'all thoughts, any of u guys have experience or info, please share it!!!
Sent from my SAMSUNG-SM-G890A using Tapatalk
Stimulates hgh and IGF.
Ibutamoren increases growth hormone levels by mimicking the action of the hormone*ghrelin*and binding to one of the ghrelin receptors (GHSR) in the brain. Activated GHSR stimulates growth hormone release from the brain.
GHSR is found in brain regions that control appetite, pleasure, mood, biological rhythms, memory, and cognition. Therefore, we can expect that ibutamoren may also affect these functions. However, so far, clinical studies describe only the effects ibutamoren has on*appetite – and as expected, like ghrelin, ibutamoren increases it.
A great thing about ibutamoren is that it increases growth hormone levels with little or no increase in other hormones, such as cortisol. Cortisol suppresses the immune system, reduces wound healing, and impairs learning and memory, and it’s usually not good to have this hormone elevated.
Optimize your levels and keep them balanced by testing blood levels.
Ibutamoren can increase growth hormone,*IGF-1, and*IGFBP-3*levels in children with growth hormone deficiency. Furthermore, these effects are achieved without changing the concentrations*of prolactin, glucose, triiodothyronine*(T3),*thyroxine*(T4), thyrotropin,* cortisol or insulin.
In severely GH-deficient men, ibutamoren increased IGF-1 and growth hormone, with no significant changes in cortisol, PRL, and thyroid hormone levels. However, insulin and glucose were increased.
After a quick run down of MK677 what are y'all that use it dosing it at??
I have read 25mg too much, makes tired and increases weight with hunger and water retention. And if taken at night that sleeping not as well with often waking up with vivid dreams...
On other hand taking in morning sleep is great at night but lethergy bad in day.
12.5mg mk677 taken in morning seems to be better result for sleep at night and aiding in anti-aging with little to no sides only benifits. Also that this dose or a smaller dose great with 2iu of hgh and increases levels of IGF and hgh thru out alone and with 2iu hgh the spike added to and one can benifit like taking 4iu Hgh with combo.
Or 2iu a day Hgh benifits from 12.5mg dose. I read alot on road so started this off here to see what u guys think before doing a big write up on info, studies, and bros doing bloods on it....
My wife wants to try 12.5mg a day for benifits of anti-aging, fat loss and healing.
I am interested in using it too but with 2-3iu hgh..
I am more than sure that IGF 1 lr3 IM would or could be more of benifit with thoughts of receptors maybe open because liver is manufacturing igf in this period?? Don't know just a thought. I like IGF 1 lr3 with hgh timing igf at hgh peak during workout.
Tell me y'all thoughts, any of u guys have experience or info, please share it!!!
Sent from my SAMSUNG-SM-G890A using Tapatalk
