Thread: Laxogenin

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    Default Laxogenin

    What is 5a-Hydroxy Laxogenin?

    Derived from plants, this ingredient is essentially an anabolic building block which your body uses as a blueprint to create its own anabolics. Laxogenin supports increased protein synthesis and nitrogen retention, while promoting other anabolic effects such as increased strength, muscle endurance, muscle recovery, and lean muscle mass. Additionally, Laxogenin aids in controlling the stress hormone cortisol, which when out of balance, can increase fat and muscle wasting.


    What does Laxogenin do?

    -Laxogenin helps increase protein synthesis by over 200% which allows the user to accelerate muscle growth and recovery .


    -Provides cortisol support, thus allowing your body to recover fast and reduces muscle breakdown (muscle wasting).


    -Athletes claim to have seen strength increases in 3-5 days, and muscle mass increases in 3-4 weeks.


    -Does not alter the users natural hormonal balance (does not affect testosterone levels and does not convert into estrogen or cause the bodyís natural estrogen to increase)


    -Does not show up on narcotic or anabolic drug screens or drug tests (can be used by Athletes in NCAA and other major league sports)



    How long can Laxogenin be cycled for?

    Laxogenin can be cycled for a period of 4, 8, or 12 weeks before having to cycle off for 4 weeks.



    Do I need cycle support?

    Laxogenin does not require a cycle support as it is not liver toxic and does not cause the user's blood pressure to fluctuate.


    What is the most effective dose for Laxogenin?

    The clinical dosage for Laxogenin is 100 mg per day.



    *Do I need a Post Cycle Therapy (PCT) after using a Laxogenin Product?

    Laxogenin does not require the use of a PCT or SERM as it is a NON-HORMONAL anabolic agent. A user will just have to simply cycle off of it for a period of 4 weeks before beginning another cycle of Laxogenin.



    Do I need an estrogen blocker when using Laxogenin?

    The use of an estrogen blocker will not be necessary as Laxogenin does not convert into estrogen, nor will it cause your body to upregulate its own estrogen production. Thus, completely eliminating the need for an estrogen blocker. You will only require an estrogen blocker if you choose to stack Laxogenin with other anabolic supplements whom have effects on the bodyís natural hormonal balance (i.e. test boosters, prohormones, etc).


    What can I stack Laxogenin with?


    Laxogenin can virtually be stacked with anything!

    -Prohormones

    -PCTs

    -Test boosters

    -Fat burners

    -Creatine

    -Other natural anabolics


    Are there any side effects to Laxogenin?

    There have been ZERO reports of side effects when using Laxogenin thus far.



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    Lifters are always in pursuit of bigger and*better gains. If thereís something they can eat, drink, or sleep on, athletes will pay hand over fist to get their hands on it. But there comes a point when many lifters give pause - injectable anabolics, a.k.a. steroids.

    Sure, when advised to take creatine, betaine, beta alanine, and BCAAs, athletes are all for it. But when the thought of embracing the unnatural means of getting huge is on the table, more than a few shun the prospect.

    Related -*The Best Testosterone Booster

    And thereís nothing wrong with that. Not everyone is comfortable injecting themselves with some type of synthetic pharmaceutical compound just for the sake of growing a bigger bicep or outer quad sweep.

    In recent years, thereís been word of an all-natural alternative to designer steroids that carries with it the increased growth and recovery of injectable anabolics, but without the concerns of altered hormone production and shrunken testicles. That alternative is laxogenin.

    Itís received some mighty high praise, billed as the next supreme muscle builder. But does it actually deliver on its hype? Letís dig down a little deeper into this mysterious sounding compound and see what it has to offer those in pursuit of endless gains.


    Laxogenin. Itís a naturally occurring steroidal sapogenin taken from Smilax Sieboldii, a plant related to asparagus, and is similar in structure to ecdysterone, another widely supplemented plant-derived anabolic compound.

    Laxogenin belongs to a family of plant-based steroids collectively known as brassinosteroids, which are present in varying quantities in the seeds, leaves, and pollen of a number of plants and foods. Interestingly enough, itís also found in high amounts in mustard oil.

    Interest in laxogenin was initially sparked after researchers discovered it demonstrated growth-promoting properties in plants. Upon seeing this, researchers began to dig deeper into the plant steroid and were astonished to learn that laxogenin actually possesses an anabolic/androgenic ratio similar to that of Anavar (Oxandrolone), one of the popular and powerful steroids of all time!

    However, unlike the synthetic steroid, laxogenin is all natural and non-hormonal, which means it doesnít put you at risk for the potential liver damage and other health consequences that come with anabolic steroid abuse.

    How Does Laxogenin Work?

    So, youíre probably thinking that since laxogenin touts a similar anabolic/androgenic ratio to that of Anavar, the two probably work fairly similarly, right?

    Wrong!

    Remember, laxogenin is a naturally-occurring, plant-derived substance, not a synthetic steroid concocted in some pharmaceutical laboratory. On top of that, there has been a substantial lack of research surrounding the actual mechanism behind laxogeninís mechanism of action.

    In other words, scientists still donít know exactly how laxogenin does what it does. But, what it does do, according to the initial studies conducted in Russia, is significantly increase muscle protein synthesis, as much as 200! Laxogenin has also been found to substantially reduce protein breakdown.*[1][2][3]

    Additionally, some other info about the effects/actions of laxogenin can be gleaned from the patent application for the ingredient.*[4][5]*Specifically, the patent application states that laxogenin can exhibit adaptogenic traits, helping your body ďnormalizeĒ its stress response.*[4]

    Additionally, it also claims laxogenin can synergize with other anabolic compounds, including anabolic steroids.*[4][5]*On top of that, itís also stated that the potent plant steroid can improve injury recovery, reduce pain, and improve cholesterol levels.*[4][5]

    Suffice it to say that laxogenin has the potential to be some pretty incredible. The problem is, is that there is a severe lack of readily available scientific research demonstrating this wealth of benefits.

    Jumping back to anavar for a minute. Itís MOA is actually known. Research notes it lowers Sex Binding Globulin (SHBG) hormone and enhances nitrogen retention, which leads to greater free testosterone levels. This all results in significantly greater anabolism (muscle growth).

    Additionally, anavar has been documented to activate lipolysis, the bodyís natural fat burning mechanism, as well as enhance thyroid hormone T3 utilization. Anavar also increases red blood cell count, promoting greater muscular energy and endurance, and lowers thyroid-binding globulin, which supports optimal thyroid function.

    Benefits of Laxogenin

    Suppose youíre not interested in the inner workings of laxogenin, and couldnít care less about its similarity to Anavar. Youíre just interested in what it can offer you. So, hereís a list of the purported benefits attributed to laxogenin usage:

    Increased protein synthesis and lean massDecreased stressEnhanced recoveryGreater strength & powerRegulates cortisol levelsAnalgesic (relieves pain)Improves blood sugar regulationReduces LDL ďbadĒ cholesterolImproves thyroid functionLimits protein breakdownCombats inflammationLaxogenin Dosing

    Due to the lack of human research on laxogenin, researchers have yet to identify a recommended daily dose of laxogenin to get the benefits listed above. That being said, anecdotal accounts of laxogenin supplementation report that benefits begin to show when consuming 100-200mg per day.

    Note that itís best to split your doses up throughout the day (morning and night) as taking over 100mg laxogenin at one time has been known to give users headaches.

    Post Cycle Therapy (PCT) is NOT required with laxogenin as it is non-hormonal.

    Quality Concerns

    Should you be interested in purchasing a laxogenin supplement, one thing to be aware of is that not all laxogenin supplements are created equally. In fact, there is a rampant use of cheap raw materials by many supplement companies, with some laxogenin products containing as little as 20-55% of the compound.

    For this reason, itís imperative to source your laxogenin supplement from a company that provides 3rd party lab tests and/or uses the HPLC-tested Laxosterone form of laxogenin which is guaranteed to contain 98% pure laxogenin.

    Bioavailability

    Laxogenin also suffers from the same problem as many other plant-based muscle builders, such as epicatechin, poor bioavailability when supplemented orally. In other words, your body isnít really utilizing all of what youíre putting in it.

    A way to enhance the bioavailability of laxogenin is to use a microencapsulated form, such as Laxosterone, or a laxogenin supplement that uses some form of delivery technology, such as liposomes or Cyclosome.

    Stacking

    Since laxogenin is non-hormonal, it can be seamlessly woven into any natty muscle building stack, and can be used alongside any/all of the following natural muscle builders:

    Beta alanineBetaineCreatineEpicatechinPhosphatidic acidBCAAsEAAsPre-workoutsIntra-workoutsNatural*testosterone boostersTakeaway

    Laxogenin offers some pretty intriguing benefits according to the preliminary studies conducted on the compound. However, the lack of substantial research and the questionable bioavailability of the ingredient keep it from being a bonafide home run.

    Is it a ďmust haveĒ ingredient? Not at all.

    But, if youíve run the course with the likes of creatine, betaine, and all the other natty muscle builders and looking for something else to ratchet up your gains, laxogenin is worth trying once or twice. Then, you can decide for yourself if itís a stud or a dud!!



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    I do not understand why Laxogenin always got a bad rep on other forums. I have taken it before and say it definitely works for me especially at 400mg. I was hungry all day haha. Quick Recovery and Strength increase as well.
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    Your the first and only person i have seen who said they used it.
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    Author: Ben Presser
    Ph.D. P.E.D. Kinesiology
    Intramuscular Injection Certified

    Aromatase Inhibitors, Post Cycle Therapy, Stenabolic, GW, Osta, LGD, S4 and IGF 1 Store

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    Quote Originally Posted by Presser View Post
    Your the first and only person i have seen who said they used it.
    Thats shocking lol. I didn't even know what it was until a friend mentioned it to me. Look to good to be true but, I can honestly say it helps out. I even have another mate taking it as well who is on the force. Its great because its not something that is banned in NCAA or police tests.
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    I love quotes like this one "Remember, laxogenin is a naturally-occurring, plant-derived substance, not a synthetic steroid concocted in some pharmaceutical laboratory".

    Isn't most pharmaceutical grade test made from wild yams? Joe Rogan keeps repeating this so it must be true!!
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    I never tried it, local supp shop says it's good stuff... don't know, i would try it, it's safe..

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    Quote Originally Posted by Muscle mechanic View Post
    I never tried it, local supp shop says it's good stuff... don't know, i would try it, it's safe..

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    I would say give it a shot.
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    Any brand that seems to be better than another?
    Get It Done!

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    Quote Originally Posted by drtbear1967 View Post
    Any brand that seems to be better than another?
    Yes, being supps aren't regulated like drugs... there is always that knuckle head using stuff low on quality and purity.
    I would use brand my local shops have but they not cheap... like 60$ bottle
    But online markets supp shops have top brands for cheaper!!!

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    Quote Originally Posted by drtbear1967 View Post
    Any brand that seems to be better than another?
    Personally being using Hi-Tech Pharmaceuticals or EPG. Hi-Tech Laxogenin is better deal though.
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    Picked up some today Bio-Genix
    GW 501516 10mg
    Laxo-genin 25mg

    Really grabbed for GW my lipids were bad last round and even I swore off never taking GW again, I want lipids good.
    Next grabbing TUDCA off Amazon!!!! Clearing bile!!

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    Would love to continue to hear your reviews on LAXO. Forgive me but I am still very much a skeptic.
     

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    Quote Originally Posted by Ashop View Post
    Would love to continue to hear your reviews on LAXO. Forgive me but I am still very much a skeptic.
    I need to try at full strength.
    My 25mg dose with 10mg GW not enough.


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    I find Laxo to greatly help in the joint health and recovery overall arena more so than straight muscle building per-se. It's another small piece to the puzzle if you wanting a natural supplement but you can only expect so much from such.
     

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    I would recommend at least taking 200mg a day personally I take 400mg .
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