It's pretty well documented that orals (17aa) elevate liver enzymes and with extended use in some individuals this can lead to liver disease(s). This isn't media flare, rather commonly held medical knowledge. You can google studies for days that supprt this. But of course, every individual is different and use, not abuse is key. I can tell you I've experienced eleveated liver problems using Tbol (while drinking) and dbol (sober). The dbol was horrific; I couldn't eat, I was always throwing shit up, my energy was low. I got some milk thistle, liquid Liv 52, ceased the dbol, and began drinking a gallon of water a day. Within a week I was back to normal. Now I know better than to take all those precautions all the time! what an idiot, I was!