Say what?
PGF2a usually comes in a 5mg/ml concentration.
Its best to start off with a dose of 2.5mg (or less!) done twice a day, 5 days a week. Thats 1/2cc at a time, or 50IUs on a slin pin
From there Id suggest you begin with increasing frequency rather than dose, heres why:
1) PGF2a has a terribly short half life. Youd be better off shooting several small doses than shooting few, but big doses.
2) PGF2a'a sides are totally dose dependent. The higher the dose, the more of the sides your going to experiance. Again, PGF2as half life is very short, so the sides you experiance will subside about an hour or two after you shoot. Basically what Im saying is more frequent use is not very likely to cause an increase in the severity of sides, however an increased dose will.
By the time you reach 4-5 doses a day, then you may consider tinkering with doses. Most people achive great results with just shooting 2.5mg to 3.75mg at a time. At a full 5mg a dose the sides will likely be severe and not longer worth the effort.