Dnp

[Doctor9]

Ok Dr. Well speaking from one Biochemist to a chemist how in the hell can you think that water is a good example?! But I'll run with it. Fill a bottle with water and then freeze it. See if it occupies the same space. Now the same thing applies to DNP crystal vs. powder. Far more crystalline DNP will fit in a 00 cap than powder.
Save the "Doctor" username for someone who at least graduated basic chemistry. I went to FSU. Did your college have a physical location?
Also what is your interpretation of "not long ago". They stopped in 1938!! On that time line my great grandmother was a hot piece of ass "not that long ago"

Firstly, the "Doctor" username is not a medical reference, but a Doctor Who one Secondly, I have a B.Sc. Chemistry from a real physical university. I would never have presumed that anyone would cap based on volume, due to the variability of bulk density. There is no way to be accurate in that manner. You need to establish a *known* bulk density/concentration to be able to do that, or, cap by mass. You'll notice water was a good example, yes, the volume changes, but the mass is the same. The reference book which I no longer have had prescription guidelines in the 50s, so it may not have completely stopped in 1938. Yes, I know, that's 60 years ago - but it's still not that long ago. There are very likely people alive who were prescribed it at one point. No hard feelings - like nearly everything, my opinions are based on my personal perception of the situation - mass versus volume. If you're capping based on volume, no kidding, crystaline material is denser....

It's still admittedly a tricky little product, and I do know people who have done it and stupidly taken too much - fortunately for them, hospital services are free under Medicare in Canada.....

Doctor9

 

[The Dude]

Firstly, the "Doctor" username is not a medical reference, but a Doctor Who one Secondly, I have a B.Sc. Chemistry from a real physical university. I would never have presumed that anyone would cap based on volume, due to the variability of bulk density. There is no way to be accurate in that manner. You need to establish a *known* bulk density/concentration to be able to do that, or, cap by mass. You'll notice water was a good example, yes, the volume changes, but the mass is the same. The reference book which I no longer have had prescription guidelines in the 50s, so it may not have completely stopped in 1938. Yes, I know, that's 60 years ago - but it's still not that long ago. There are very likely people alive who were prescribed it at one point. No hard feelings - like nearly everything, my opinions are based on my personal perception of the situation - mass versus volume. If you're capping based on volume, no kidding, crystaline material is denser....

It's still admittedly a tricky little product, and I do know people who have done it and stupidly taken too much - fortunately for them, hospital services are free under Medicare in Canada.....

Doctor9

I think we may be looking at this from two different viewpoints and that is the issue. I agree that if this product were available from a legitimate pharmacy through a real Dr, it may be somewhat safer, however I still believe it is riskier than pretty much anything else. Phenols are carcinogenic and DNP has been shown to cause cataracts. I've searched and found nothing (not really surprising given its obscurity) that can counteract the outcome of an overdose.
The real issue here is that this is a somewhat rare black market bathtub drug. I recently had a very trusted source give me 170mg/ml test prop labelled as 100mg/ml of test prop. Pretty cool on that front, but imagine if that were DNP. Or let's say our rocket scientist source is used to eyeballing his caps with a certain amount of DNP and his deliveries were always powder. Then he gets a shipment of crystal and eyeballs a couple of these (if not all) and sends them out. This kind of thing happens all the time with AAS and with veteran users. Given the relative obscurity and potential for disastrous sides IMO it just isn't even close to being worth it.
Imagine you call paramedics and say "I took too much DNP". You'd be dead before you could finish explaining to them what it is, let alone the time it would take to research it and find a way (if there is one) to counteract it.
This isn't something like insulin where some super sugar water is going to pull you out. You are completely destroying the Krebs cycle at the cellular level and throwing off the energy your body is trying to produce as body heat with no cap on the temp you reach (until you're med well and more of a steak than a man).
That's my simple point. There's no return for a single dose screw up.

 

[big in vegas]

This is one thing that I swear I will never touch. I'm afraid of slin, but I'll probably eventually try that, but this shit is completely out of the question

 

[the_anapolack]

The uncoupling agent 2,4-dinitrophenol improves mitochondrial homeostasis following striatal quinolinic acid injections.
Korde AS, Sullivan PG, Maragos WF.
Source
Department of Neurology, University of Kentucky, Lexington, KY 40536-0284, USA.
Abstract
It is now generally accepted that excitotoxic cell death involves bioenergetic failure resulting from the cycling of Ca2+ and the generation of reactive oxygen species (ROS) by mitochondria. Both Ca2+ cycling and ROS formation by mitochondria are dependent on the mitochondrial membrane potential (Deltapsi(m)) that results from the proton gradient that is generated across the inner membrane. Mitochondrial uncoupling refers to a condition in which protons cross the inner membrane back into the matrix while bypassing the ATP synthase. As a consequence of this "short-circuit," there is a reduction in Deltapsi(m). We have previously demonstrated that animals treated with the classic uncoupling agent 2,4-dinitrophenol (DNP) show significant protection against brain damage following striatal injections of the NMDA agonist quinolinic acid (QA). In an effort to elucidate the mechanism of neuroprotection, we have assessed the effects of DNP on several parameters of mitochondrial function caused by QA. The results presented herein demonstrate that treatment with DNP attenuates QA-induced increases in mitochondrial Ca2+ levels and ROS formation and also improves mitochondrial respiration. Our findings indicate that DNP may confer protection against acute brain injury involving excitotoxic pathways by mechanisms that maintain mitochondrial function.