Baylor University just conducted a study, which some have referenced it as “Resistance exercise intensity does not differentially affect skeletal muscle myostatin gene expression but does increase serum myostatin propeptide levels.”.
In this study, they took a group of weight trainers and had them go through several leg workouts.
What they did was perform exercises like the leg press and the leg extension.
However, they did each exercise 1 leg at a time.
For both legs they had them perform the same amount of sets and exercises, but on one leg they had them perform sets of 6 reps, and the other leg sets of 20 reps.
The scientists then took blood samples and muscle biopsies of each leg after every workout training session.
What did they find?
They discovered that the leg that performed the sets of 6 reps (low reps / heavier weight) had 3 times higher the amount of myostatin than the leg that performed sets of 20 reps (high reps / lighter weight).
“What’s myostatin?”, you may be asking.
Myostatin is a protein that limits the amount of growth in muscle tissue and fibers.
The higher the amount of myostatin in a muscle, the less amount of size it can gain.
So, obviously, if gaining weight and building muscle mass is our goal, myostatin is our enemy.
We don’t want raised levels of this protein!
So, according to this study, training with heavier weights for lower reps raises the levels of myostatin in the muscle being trained 3 times higher than lower weight for higher reps, resulting in limited growth.