Recommended StorageUnopened Novolin R vials should be stored in the refrigerator (36° - 46°F [2° - 8°C]). If carriedas a spare or if refrigeration is not possible, unopened Novolin R vials can be kept at room temperatureprovided they are kept as cool as possible (not above 77oF [25oC]). If kept at room temperature, NovolinR vials must be discarded after 42 days even if they are unopened.Do not freeze and do not use Novolin R if it has been frozen. In addition, unopened NovolinR vials should be kept in their cartons so that they will stay clean and protected from light. They shouldnot be exposed to heat or light.An opened (In use) Novolin R vial can be kept at room temperature provided it is kept as cool aspossible (not above 77oF [25oC]) and away from heat or light. Do not refrigerate after first use.Unopened and opened (In use) Novolin R vials must be discarded 42 days after they are firstkept out of the refrigerator, even if they still contain Novolin R insulin.Table 9: Storage Conditions for Novolin R vialsUnopened(Refrigerated)Unopened(Room Temperature up to 77oF [25oC] )Opened (In use)(Room Temperature up to 77oF [25oC])Until expiration date 42 days* 42 days** The total time allowed at room temperature (up to 25oC) is 42 days regardless of whether the product is unopened oropened (In use)Infusion bags prepared as indicated under DOSAGE AND ADMINISTRATION (2.3) are stable atroom temperature for 24 hours. A certain amount of insulin will be initially adsorbed to the material ofthe infusion bag.Always remove the needle after each injection. Always use a new disposable syringe and needlefor each injection to prevent contamination.Never use insulin after the expiry date which is printed on the label and carton.