MC IGF1 LR3 is the real deal incredible!

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MC IGF1 LR3 is the real deal incredible!

You can see and feel it working, makes other IGF LR3 products look like shit!


One igf is no better than another, its either real or its not or your getting plain old igf-1 , which when without the arginine blows!

A distinct biological advantage
All mammalian cells secrete IGF Binding Proteins (IGFBPs) which bind to and inhibit native IGF-I. The substitution of an arginine for glutamic acid at position three in LONG®R3 IGF-I, in conjunction with the 13 amino acid N-terminal extension peptide, results in > 1000 fold reduced affinity for IGFBPs, enhancing its bio-availability and effectiveness in comparison to native IGF-I.

Specificity is the key to increased productivity
Unlike insulin, LONG®R3 IGF-I specifically targets and activates the type I IGF Receptor (IGF-IR) resulting in greater activation of downstream signaling cascades responsible for proliferation and inhibiting apoptosis. Greater activation of these key pathways results in increased cell density, higher viability and extended cell culture productivity.

To learn more about the use of LONG®R3 IGF-I in stem cell and cell therapy applications, please contact Repligen.
 



One igf is no better than another, its either real or its not or your getting plain old igf-1 , which when without the arginine blows!

A distinct biological advantage
All mammalian cells secrete IGF Binding Proteins (IGFBPs) which bind to and inhibit native IGF-I. The substitution of an arginine for glutamic acid at position three in LONG®R3 IGF-I, in conjunction with the 13 amino acid N-terminal extension peptide, results in > 1000 fold reduced affinity for IGFBPs, enhancing its bio-availability and effectiveness in comparison to native IGF-I.

Specificity is the key to increased productivity
Unlike insulin, LONG®R3 IGF-I specifically targets and activates the type I IGF Receptor (IGF-IR) resulting in greater activation of downstream signaling cascades responsible for proliferation and inhibiting apoptosis. Greater activation of these key pathways results in increased cell density, higher viability and extended cell culture productivity.

To learn more about the use of LONG®R3 IGF-I in stem cell and cell therapy applications, please contact Repligen.


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