Follow along with the video below to see how to install our site as a web app on your home screen.
Note: This feature may not be available in some browsers.
Yoda is pretty much on point with his statement... The only thing I'll add to that, is that when taken by injection, the compound is filtered at a lower rate, through the liver(thus slightly lowering hepatotoxicity from a bolus dose.... But the same amount of compound still has to be metabolized by the liver, just at a different rate than orally). Also, to clear up yoda interpretation of liver metabolism, ph are metabolized by liver in the same ways as aas. There is extensive metabolization by the liver, and by other organs/tissues... It's more than a 'one pass' or 'two pass' type of system... Either way, it's very similar for both ph and aas...
Yes, basically that is true... There is small variances in HIGHLY toxic substances, that make them SLIGHTLY more tolerable, for very short periods of time(methyltren is what comes to mind for an example of this... It's highly toxic, yet is tolerated for VERY short runs, at a dose roughly 3x higher than what could be tolerated orally... 1.5mg/day for 2 weeks vs 500mcg/day at two weeks...). That is an example that I can think of as an exception to the rule... But that's what it is, is an exception... Methyltren is actually used by researchers to cause liver failure in rats... Part of it's action is due to the bolus dose(all at once) hitting the liver...
That would be my problem with this report as well as the Arginine one... They are realistically impossible circumstances... 10grams all at once on a rats pancrease will piss it off I am sure lol 3 grames of methyl compounds on a liver all at once in a rat will piss its liver off too... those aren't realistic real world applications... at the same time it's rats... we are much more resilient then they are. I am by no means taking away from what your saying, we both are saying the same thing about this thread, but I'd like to see it more based off of human consumption and studies verses bolus doses in rats... this little tangent probably would have fit better in the Arginine thread... I'm just saying bolus doses in rats doesn't equal intelligent use by humans.