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Written by George N. Touliatos, MD
Testosterone Replacement: Subcutaneous Injections vs. Intramuscular
By George Touliatos, MD
Q: Is there any benefit of subcutaneous injections of testosterone replacement?
A: Sub C shots have the benefit of being injected into the fat under the skin. In this way, there is no scar tissue creation like when we inject deep into the muscle in the case of an intramuscular (IM) injection. Sub C injections are performed with an insulin needle that is 31 gauge, which is tiny. The disadvantage of subcutaneous injections is the poor blood supply of adipose tissue. This leads to slower absorption of the substance, compared to IM shots. Another speculation is that injected testosterone into the fat will be more likely to aromatize, especially in men who are overweight. However, this theory doesn’t exist. The fact is that testosterone is no longer active until it is separated from the ester (cypionate, enanthate, propionate, undecanoate). Therefore, it’s converting to estrogen after its separation when it is already in the bloodstream. Another disadvantage of the subcutaneous injection is the creation of poly lumps under the skin, especially in lean men with single-digit body fat percentage (six-pack).
Watch E 156 of Ask Dr. Testosterone with Special Guest: Andre Miller, of Frontline Alternative Medicine HRT
George Touliatos, MD is an author, lecturer, champion competitive bodybuilder and expert in medical prevention regarding PED use in sports. Dr. Touliatos specializes in medical biopathology and is the medical associate of Orthobiotiki.gr and Medihall.gr, Age Management and Preventive Clinics in Athens, Greece. Heis the author of four Greek books on bodybuilding, has extensively developed articles for www.anabolic.org and is the medical associate for the book Anabolics, 11th Edition (2017). Dr. Touliatos has been a columnist for the Greek editions of MuscleMag and Muscular Development magazines, and has participated in several seminars across Greece and Cyprus, making numerous TV and radio appearances, doing interviews in print and online. His personal website is https://gtoul.com/
Click here to view the article.
Testosterone Replacement: Subcutaneous Injections vs. Intramuscular
By George Touliatos, MD
Q: Is there any benefit of subcutaneous injections of testosterone replacement?
A: Sub C shots have the benefit of being injected into the fat under the skin. In this way, there is no scar tissue creation like when we inject deep into the muscle in the case of an intramuscular (IM) injection. Sub C injections are performed with an insulin needle that is 31 gauge, which is tiny. The disadvantage of subcutaneous injections is the poor blood supply of adipose tissue. This leads to slower absorption of the substance, compared to IM shots. Another speculation is that injected testosterone into the fat will be more likely to aromatize, especially in men who are overweight. However, this theory doesn’t exist. The fact is that testosterone is no longer active until it is separated from the ester (cypionate, enanthate, propionate, undecanoate). Therefore, it’s converting to estrogen after its separation when it is already in the bloodstream. Another disadvantage of the subcutaneous injection is the creation of poly lumps under the skin, especially in lean men with single-digit body fat percentage (six-pack).
Watch E 156 of Ask Dr. Testosterone with Special Guest: Andre Miller, of Frontline Alternative Medicine HRT
George Touliatos, MD is an author, lecturer, champion competitive bodybuilder and expert in medical prevention regarding PED use in sports. Dr. Touliatos specializes in medical biopathology and is the medical associate of Orthobiotiki.gr and Medihall.gr, Age Management and Preventive Clinics in Athens, Greece. Heis the author of four Greek books on bodybuilding, has extensively developed articles for www.anabolic.org and is the medical associate for the book Anabolics, 11th Edition (2017). Dr. Touliatos has been a columnist for the Greek editions of MuscleMag and Muscular Development magazines, and has participated in several seminars across Greece and Cyprus, making numerous TV and radio appearances, doing interviews in print and online. His personal website is https://gtoul.com/
Click here to view the article.
