Acth 1-39 & aicar

Hi guys i need some help out here i'm using Igf-1 lr3/Igf-2 20mcg PW day then 36 hours MGF and MGF/Pgy pre W 1 day 200mcg ea with 4 ui HG 6 day week & i just received ACTH & AICAR any one knows a protocol for the ACTH & AICAR to be Used with HG & IGF-1 segment i'm going crazy here my guinea pig is getting irritated already..... he's endurance runner,, i'm running 45 days, 36 hours protocol for the Igf mgf and 12 weeks for Hg so i need my guinea pig to get ready in 12 week anyone out there that can help me with this please...
thanks in advance:dizzy:,

Sorry bro but I have no knowledge of this peptide. I like running the irg2/3 combo, whats your subjects dosing protocol? results? Id like to hear!

Are you sure you want to use ACTH and AICAR? ACTH is Adrenocorticotropic hormone which increases androgens, but it also causes the secretion of cortisol--that's something you really don't want. AICAR has been used in studies where they gave it to mice, and it converted fast-twitch muscles into slow-twitch muscles. I suppose maybe that could be a good thing for an endurance runner, since that's the main kind of muscle fiber used for endurance running.

References on AICAR

^ Corton JM, Gillespie JG, Hawley SA, Hardie DG (April 1995). "5-aminoimidazole-4-carboxamide ribonucleoside. A specific method for activating AMP-activated protein kinase in intact cells?". Eur. J. Biochem. 229 (2): 558–65. doi:10.1111/j.1432-1033.1995.0558k.x. PMID 7744080.

^ Lemieux K, Konrad D, Klip A, Marette A (September 2003). "The AMP-activated protein kinase activator AICAR does not induce GLUT4 translocation to transverse tubules but stimulates glucose uptake and p38 mitogen-activated protein kinases alpha and beta in skeletal muscle". Faseb J. 17 (12): 1658–65. doi:10.1096/fj.02-1125com. PMID 12958172.

^ Kim JE, Kim YW, Lee IK, Kim JY, Kang YJ, Park SY (March 2008). "AMP-activated protein kinase activation by 5-aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside (AICAR) inhibits palmitate-induced endothelial cell apoptosis through reactive oxygen species suppression". J. Pharmacol. Sci. 106 (3): 394–403. doi:10.1254/jphs.FP0071857. PMID 18360094.

^ Narkar VA, Downes M, Yu RT, Embler E, Wang YX, Banayo E, Mihaylova MM, Nelson MC, Zou Y, Juguilon H, Kang H, Shaw RJ, Evans RM (August 2008). "AMPK and PPARdelta agonists are exercise mimetics". Cell 134 (3): 405–15. doi:10.1016/j.cell.2008.06.051. PMID 18674809.

thanks for the help guys,, yes i agree with you " Saudades" but they are using and some how taking the benefit of it, and stacking it with something else, just like [FONT=&quot]S[/FONT][FONT=&quot]elective[/FONT][FONT=&quot]A[/FONT][FONT=&quot]ndrogen[/FONT][FONT=&quot]R[/FONT][FONT=&quot]eceptor[/FONT][FONT=&quot]M[/FONT][FONT=&quot]odulator or SARM's[/FONT] why no one is talking about a dosing protocol for SARM to be Used with IGF /MGF/HGH and sermorelin man some times i feel like we're always left behind......
well guys we are just a little to late from the Europeans, they are freaking using it already from a while back. but no one publish their protocol, it so secret until it actually come out, it will be 3 to 5 years and they are way ahead of us. just like the sermorelin they were using it more then 5 years ago and the AICAR 1-39 used with IGF-1 /IGF-2 MGF/ MGF pgy HGH dosing protocol,,,, but all of the info that i got from there they are not telling the whole thing, and some from Australia i'll have hole in my pocket, maybe then my Guinea pig gets dead strong heheheeh.........
i still need the info if anyone got a dosing protocol please post it


thanks for the info SAUDADES

regarding aicar, the dose suggested to me was 100mg 3-4 times a week. and I totally agree with you tom, people are using these drugs and their are dosage protocols out there. it might take some time for people to work out their own regimen. suppliers are out there and its a lot more obtainable than people may think.

You're welcome, tomdado.

I would also agree that all these new things are being used out there--probably have even been used for a while, but because of the way our government is, we never have access to them. There are guys in Europe already using the the myostatin vaccine for crying out loud. I wish Congress would stop meddling in our lives as if we can't decide what's good for ourselves.

If the European guys are using the myo vaccine watch out for some huge guys coming from that way.

OK guys here we are
this is my take on Aicar & GW1516 here is my take on this shit,,, and i mean piece of shit i spent a lot of money for 3 of my guinea pig friends and my own guinea pig... all of them allready had a great performance... no possitive signs of making any better performance then already had... i mean nothing after 3 months.... but but look out for the damages done to those body ....
look ou for the HDL to go seriously low careful or you'll have some serious problems... heart palpitation and serious Arrhythmia Possible symptoms of a common type of arrhythmia, a trial fibrillation, include heart palpitations, dizziness, and chest pain pinching and other </SPAN>

it decreased VO max in all 4 of them
it seams to run out stamina faster than normal, recovery prolonged the time, it seams that lungs and heart was affected by it…
so overall performance has not been enhanced
on the other hand it has damaged performance in all 4 guinea pig
protocol followed was 1 month 2 time a week 100mg
no improvement but loss of performance was seen then
change protocol to 3 times a week same thing happen.
Then third month change protocol to 8 days 13 mg a day 2 days of,, for 40 days.
Same shit loss of performance…..
Some is not right with this crappie product some has to be changed… some is not right for sure
My advice stay a way from it for the moment until they get it right…

tomdado3009 said:

OK guys here we are
this is my take on Aicar & GW1516 here is my take on this shit,,, and i mean piece of shit i spent a lot of money for 3 of my guinea pig friends and my own guinea pig... all of them allready had a great performance... no possitive signs of making any better performance then already had... i mean nothing after 3 months.... but but look out for the damages done to those body ....
look ou for the HDL to go seriously low careful or you'll have some serious problems... heart palpitation and serious Arrhythmia Possible symptoms of a common type of arrhythmia, a trial fibrillation, include heart palpitations, dizziness, and chest pain pinching and other </SPAN>

it decreased VO max in all 4 of them
it seams to run out stamina faster than normal, recovery prolonged the time, it seams that lungs and heart was affected by it…
so overall performance has not been enhanced
on the other hand it has damaged performance in all 4 guinea pig
protocol followed was 1 month 2 time a week 100mg
no improvement but loss of performance was seen then
change protocol to 3 times a week same thing happen.
Then third month change protocol to 8 days 13 mg a day 2 days of,, for 40 days.
Same shit loss of performance…..
Some is not right with this crappie product some has to be changed… some is not right for sure
My advice stay a way from it for the moment until they get it right…

Click to expand...

Same post in every thread related to AICAR, seems suspicious at least.
Negative propaganda for what reason?
Hiding the truth that legit AICAR works big time, maybe?

About the ACTH thing: Cortisol is not bad. The testosterone/cortisol ratio is what we must take care of. If it is favourable during a cycle, anabolism is what we get. If we use ACTH as PCT for example, this guarantees sure muscle catabolism.

tomdado3009 said:

OK guys here we are
this is my take on Aicar & GW1516 here is my take on this shit,,, and i mean piece of shit i spent a lot of money for 3 of my guinea pig friends and my own guinea pig... all of them allready had a great performance... no possitive signs of making any better performance then already had... i mean nothing after 3 months.... but but look out for the damages done to those body ....
look ou for the HDL to go seriously low careful or you'll have some serious problems... heart palpitation and serious Arrhythmia Possible symptoms of a common type of arrhythmia, a trial fibrillation, include heart palpitations, dizziness, and chest pain pinching and other </SPAN>

it decreased VO max in all 4 of them
it seams to run out stamina faster than normal, recovery prolonged the time, it seams that lungs and heart was affected by it…
so overall performance has not been enhanced
on the other hand it has damaged performance in all 4 guinea pig
protocol followed was 1 month 2 time a week 100mg
no improvement but loss of performance was seen then
change protocol to 3 times a week same thing happen.
Then third month change protocol to 8 days 13 mg a day 2 days of,, for 40 days.
Same shit loss of performance…..
Some is not right with this crappie product some has to be changed… some is not right for sure
My advice stay a way from it for the moment until they get it right…

Click to expand...

This entire post smacks of bs. I think, first off, the doses mentioned are seriously too high. From what I've read the best way to dose AICAR, and make it affordable, is to run it with GW1516, as the act synergistically. The most quoted protocol I've seen with AICAR/GW1516 is 10mg's of each, eod, alternating. I've got both and am readying a short cycle for use soon.