Your body will attenuate to the ephedrine and caffeine faster without the aspirin. Ketotifen might work, but that may only work for Clen. If its been accepted as the best combo, why argue. I don't think it will have a synergistic effect, but they both will help you get leaner. You'll need to be more specific with your question.
It's like if I said
A one armed midget, a three toed sloth, a wombat, and a Yugo... What do you think? Lol!!