i would say, like everything else it will depend on the person. . Some people get gyno symptoms from 250ml test others go over a gram with no problems.
Personally if i were to feel any sign of gyno i will use anti.E or anti.p straight away and will continue to use it with every other cycle to ensure i never get that bitch tit shit. i would sacrifice a couple pounds (generally just water) to ensure i do not get gyno. . why risk it then have to have $$$$ surgery