Let's see if I can remember....natural blockers are:
Beta-Sitoserol (spelling?)
Phosphatidylserine
vitamin C is also supposed to help block cortisol
Here's a web link on Cushing syndrome and psychiatric issues (I don't know why it's there in a site for antiques, it just is):
http://quicksitebuilder.cnet.com/jaminantiquesandcollectables/id15.html
Text excerpt of it below--lists a few strong drugs that lower cortisol levels:
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Psychiatric Issues of Cushing's Patients
by Dori Middleman, M.D.
posted with permission from Dr. Dori Middleman
How common are psychiatric problems with Cushing's, and what problems do Cushing's patients have?
In some studies, as many as 90% of Cushing's patients suffer from depression. In part, this is due to actual chemical changes in the brain from high cortisol. The depressing effect of having a serious and impairing illness may also contribute to depression. High cortisol levels also can be experienced by the body as anxiety, and insomnia is extremely common in patients on steroids and with high cortisol states. Elevated, agitated mood, like in mania, can also be seen in a minority of patients, and some actually hallucinate and have psychotic symptoms. Problems with concentration and memory are common and may improve or continue after recovery, depending upon the severity and length of the Cushing's symptoms.
What treatments are there for Cushing's patients' psychiatric problems?
Ultimately, the most important treatment is control of the cortisol level. Thus, surgery or radiation are needed for most patients with Cushing's Disease and Cushing's Syndrome due to adrenal tumors. On a temporary basis, medications, such as
ketoconazole, metyrapone, and aminogultethimide, have been used to lower high cortisol levels due to tumors and may be helpful in alieviating some of the psychiatric symptoms associated with the high cortisol state.
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Note: The drugs listed in the excerpt are to lower cortisol, not treat for psychiatric symptoms. I just happened to find them listed in this article.