Letrozole and nolvadex cannot be used together! Nolvadex lowers the effectiveness of letrozole by 38% through an unknown mechanism. However, I know several competitors who have told me they take both concurrently Bc their "coaches" don't have a clue about drug interactions. Be smart and do your research!
I have been know this. They use same digestive cyp enzymes 450 I think.
This is with lots of things.
It's no different than using lots of drugs Dr's prescribed together.
Inhibitors block the metabolic activity of one or more*CYP450*enzymes. The extent to which an inhibitor affects the metabolism of a drug depends upon factors such as the dose and the ability of the inhibitor to bind to the enzyme.Aug 1, 200
Adex is affected as well by same cyp enzyme nolva adex and letro all interfere with.
The best bet is Aromasin are just use WHAT u need go be feel!
There is no set dose, dosing depends on aromatase and other things that use same cyp enzymes which are alot more those two!
It's not like most of us use 100% pure letro Pharma grade and the dosing is set period anyway!!!
I rather block with nolva and use less of what kills my lipids.
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