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Oxymetholone from Iran Hormone is an oral steroid that posesses very high anabolic and high androgenic properties, this oral steroid being the strongest oral known. It’s known for it’s superior strength and size gains, it’s effectiveness is just short of injectable Testosterone. Other available name for oxymetholone substance is Anadrol.
Oxymetholone was probably the all time favorite mass and strength building oral AAS. At dosages of 100-250 mg/d, many realized weight gains of 1 5-25 lbs…n only a few weeks. Users raved about unbelievable strength and recovery as well. Unfortunately, the majority of weight gain was water retention and to a much lesser extent increased red blood cell count. Post-cycle lean mass retention sucked unless a high anabolic AAS such as Nandrolone,Equipoise, Winstrol-Depot, or Primobolan Depot were stacked with it, or in my experience more wisely utilized in a Max Androgen Phase. (And Oxymetholonewas discontinued at least 10-14 days before the high anabolic of course)
Oxymetholone was commonly used the last few weeks pre-contest also. This was done to increase training intensity, post work-out recovery, increase vascularity, and induce a distinct fullness/hardening effect. When used pre-contest, Oxymetholone required the use of Nolvadex or other estrogen receptor antagonist.
Even with the use of a finasteride-type drug, Oxymetholone tended to cause balding for some. It also gave many athletes raging gyno in the upper dosage ranges. Oxymetholone does not actually aromatize but does posses progesterone like qualities. Progesterone is an estrogen that causes gyno as well as serious water retention. Faslodex (fulvestrant) has been the better estrogen antagonist during administration of any AAS with progestin activity. Why, the drug works by down-regulating estrogen and progesterone receptor counts. Less receptors means less activity. There was a debate as to whether or not Oxymetholone did, or could convert to, a DHT or DHT derivative.
Oxymetholone was such a potent androgen that it attached itself to sex tissue specific androgen receptors in the scalp and prostatic areas. Finasteride did seem to posses some receptor-site blocking qualities and therefore was helpful. Interestingly, Oxymetholone did not induce strong activation of androgen receptor-sites in muscle tissue. But it did cause impressive muscle mass gains. Ironic, but obviously Oxymetholone worked. Sadly, Oxymetholone was seriously liver toxic. Only Methyltestosterone rivaled it for toxicity and Halotestin beat it for liver destruction. Due to serious water retention during Oxymetholone use pre-contest, a diuretic would be necessary the last 2-3 days pre-contest. Remember Oxymetholone causes serious HPTA suppression.
Oxymetholone is considered by many to be the most powerful steroid available, with results of this compound being extremely dramatic. A steroid novice experimenting with oxymetholone is likely to gain 20 to 30 pounds of massive bulk, and it can often be accomplished in less than 6 weeks, with only 50-100mg a day. This steroid produces a lot of trouble with water retention, so let there be little doubt that much of this gain is simply bloat. But for the user this is often little consequence, feeling bigger and stronger on Oxymetholone than any steroid they are likely to cross. Although the smooth look that results from water retention is often not attractive, it can aid quite a bit to the level of size and strength gained.
It is known that using Oxymetholone requires a huge dose of 50mg-100mg per day to yield gains. In order to avoid the very risky side effects one should respect and not exceed the recommended dosage and cycle of maximum 4-6 weeks.
When stacking Oxymetholone with other steroids it is necessary to make sure that they are not alpha-alkylated. So it is recommended to stack Oxymetholone with anabolic agents that bind well with the ARs. In this way the bodybuilding results are guaranteed since anabolism can deliver through different mechanisms.
If you plan to stack Oxymetholone with other steroids, make sure that they are not alpha-alkylated for obvious reason. Oxymetholone has a poor binding affinity with androgen receptors thus the higher dosage practice. So it is recommended that you stack Oxymetholone with other anabolic agents the bind well with the ARs. In this manner, you are assured of great bodybuilding results since anabolism can deliver through different mechanisms. This is also a safer method since you can opt for the most conservative Oxymetholone dosage but can still acquire ideal anabolic effects.
To further its effectiveness as an anabolic agent, bodybuilders typically “stack” Oxymetholone with other anabolic steroids. Since it is already a very potent androgen, many users will only use it for the first 3-4 week of the cycle, giving time for intra-muscularly injected products such as nandrolone, boldenone and testosterone to reach maximum blood levels.
Oxymetholone Side Effects
Using Oxymetholone comes with a price, high water retention (which will attribute weight loss after completion), increased blood pressure, aromatization, liver stress, and affects upon the body’s natural hormonal levels. The side-effects of short-term use of the drug itself include nausea, bloating, acne, and masculinizing effects such as deepening of the voice, growth of facial hair and clitoral hypertrophy. In addition, unless selective estrogen receptor modulators such as tamoxifen or clomifene are taken in conjunction with the drug, there is a significant risk of the appearance of estrogenic effects such as gynaecomastia over time. Because of its 17α-alkylated structure, Oxymetholone is highly hepatotoxic. Long term use of the drug can cause a variety of serious ailments, including hepatitis, liver cancer, and cirrhosis. It is dangerous to take Oxymetholone in high dosages for periods of time exceeding four weeks, and is commonly used by bodybuilders during the start of a steroid cycle to help gain mass.
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