just use one or the other a .22 will not only filter particals but will also filter bateria and virus as well so in theroy you should have sterile gear with out the heat process..but i would still use heat to sterilize your oil-cuz u never know right..
if you are doing just raw aas you should be good to go with either as a 22 wont block up with any little bits if thats what your thinking with a 45 first..even doing tren pellets conversion ive never had a whatman 45 block up on the last filter.
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