AAS and immunity
- Thread starter dorian123
- Start date
big in vegas
MuscleChemistry Registered Member
I very rarely get sick so I can't tell you, but I haven't gotten sick while on so I can't say that it lowers it or I'd get sick.....Just pick your nose and eat it, that's the best immune system builder you can have lol
i've read that anabolics in moderate doses increase the activity of certain white blood cells causing them to become more "aggressive" towards viruses and bacteria in the body.
at higher doses they are known for decreasing the amounts of IgA, IgG, and IgM in the blood. IgA-G-M are protiens that circulate in the blood and act as antibodies. so fewer of these could lead to a decreased immune response. potentially making an injection abcess more likely if the anabolic dose is high enough....
i'll do some research to see if different doses have been studied.
at higher doses they are known for decreasing the amounts of IgA, IgG, and IgM in the blood. IgA-G-M are protiens that circulate in the blood and act as antibodies. so fewer of these could lead to a decreased immune response. potentially making an injection abcess more likely if the anabolic dose is high enough....
i'll do some research to see if different doses have been studied.
Anabolic steroid effects on immune function: differences between analogues.
Mendenhall CL, Grossman CJ, Roselle GA, Hertelendy Z, Ghosn SJ, Lamping K, Martin K.
Source
Department of Medicine, Veterans Administration Medical Center, Cincinnati, Ohio 45220.
As an untoward effect of chronic anabolic steroid use, immunologic alterations may be induced. To evaluate this possibility five commercially available steroids with various types of structural differences were studied in male Sprague-Dawley rats. Animals were divided into five groups and treated with testosterone (Group 1), testosterone propionate (Group 2), testolactone (Group 3), oxandrolone (Group 4), and stanozolol (Group 5). Androgenic anabolic steroids were administered daily, subcutaneously dissolved in oil, at a dose of 1.1 mg/kg. Immune alterations were assessed by skin-test responses to phytohemagglutinin. After five days of treatment (1.1 mg/kg/day) a significant immuno-suppression was observed with all groups. However, by day 10, groups 3, 4, and 5 showed an immuno-stimulation. Using oxandrolone as the model stimulant, serum testosterone levels were significantly suppressed, while castration abolished the stimulatory effect. These observations indicate that immune alterations do occur with anabolic steroids which are immuno-suppressive when the steroid nucleus is intact and immuno-stimulatory with nuclear alterations. It appears that these changes are associated with altered gonadal testosterone release.
Mendenhall CL, Grossman CJ, Roselle GA, Hertelendy Z, Ghosn SJ, Lamping K, Martin K.
Source
Department of Medicine, Veterans Administration Medical Center, Cincinnati, Ohio 45220.
As an untoward effect of chronic anabolic steroid use, immunologic alterations may be induced. To evaluate this possibility five commercially available steroids with various types of structural differences were studied in male Sprague-Dawley rats. Animals were divided into five groups and treated with testosterone (Group 1), testosterone propionate (Group 2), testolactone (Group 3), oxandrolone (Group 4), and stanozolol (Group 5). Androgenic anabolic steroids were administered daily, subcutaneously dissolved in oil, at a dose of 1.1 mg/kg. Immune alterations were assessed by skin-test responses to phytohemagglutinin. After five days of treatment (1.1 mg/kg/day) a significant immuno-suppression was observed with all groups. However, by day 10, groups 3, 4, and 5 showed an immuno-stimulation. Using oxandrolone as the model stimulant, serum testosterone levels were significantly suppressed, while castration abolished the stimulatory effect. These observations indicate that immune alterations do occur with anabolic steroids which are immuno-suppressive when the steroid nucleus is intact and immuno-stimulatory with nuclear alterations. It appears that these changes are associated with altered gonadal testosterone release.
The Dude
MuscleChemistry Registered Member
I can't see how something that increases your bodies ability to repair itself can possibly have a negative effect on your immune system. The simple idea is fundamentally ridiculous. Overtraining yes. HIV positive people have been living decades longer due to the accepted and widely practiced use of AAS and they are afflicted with an immuno suppressive disease. BTW I'd like to add that my BP was 117 / 72 on my last visit to the Dr. I guess steroid use doesnt automatically correlate to high BP either.
this is a very good point here, never thought of this
as for the BP I think it depends on the person and what they are running/dosages
big in vegas
MuscleChemistry Registered Member
This is what I've always heard as well
big in vegas
MuscleChemistry Registered Member
That's more or less it. If the government could make a profit off of it or control it like they do alcohol and tobacco, it'd be legal
hit they are pushing the hell out of testosterone now in commercials, just like the cialis and viagra commercials, now its "Do you have low T" ask ur doctor about.........TESTOSTERONE AND SARMS, ALL NEATLY PACKAGE PHARACEUTICAL STEROIDS, so they are making a killing off this shit,
big in vegas
MuscleChemistry Registered Member
I've not seen any of these commercials, but like dorian said, hopefully it'll change some people's perceptions although I doubt it
nah, cause they dont call it Testosterone, they call it "Low T" lol, and they package and sell the shit in a nice unobtrusive* name like SARMS, they think they are slick, well they are slick,lol, but this little doggy knows,lol
Similar threads
