I have been on TRT for a long time. I have gone all over the map in dosages. I think 200mg per week is best but I like to split it up. 200mg is probably way to much. The average dose is 100mg per week. I split it up to avoid the high spike. I read one time where a 100mg shot would put your numbers super high then of course drop down over the period of a week. To avoid that you could do 50mg every other day and it would never spike like the 100mg shot would. I don't do that, but have thought about trying. I just use 100mg twice a week. Its all about trying to get the levels stable to avoid the up and down spikes. I use cyp also.